Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
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[Homology]
Score
CF15_07910Protein methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (275 aa)    
Predicted Functional Partners:
rtcA
RNA 3'-phosphate cyclase; Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
   
    0.795
CF15_03240
ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.708
rpl30
50S ribosomal protein L30; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
   0.684
CF15_00975
ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.673
CF15_00280
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.643
CF15_01455
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.572
rps8e
30S ribosomal protein S8e; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.569
truB
H/ACA RNA-protein complex component Cbf5p; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.
   
  
 0.568
CF15_03415
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.561
CF15_02375
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.554
Your Current Organism:
Pyrodictium occultum
NCBI taxonomy Id: 2309
Other names: DSM 2709, JCM 9393, NBRC 100438, P. occultum, strain PL-19
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