Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CF15_07930Derived by automated computational analysis using gene prediction method: Protein Homology. (284 aa)    
Predicted Functional Partners:
CF15_07840
Endonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.853
CF15_00945
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.683
CF15_07605
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.683
guaA
GMP synthetase; Catalyzes the synthesis of GMP from XMP.
  
    0.667
CF15_06995
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
     
 0.656
CF15_00055
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.638
CF15_00240
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.615
CF15_04210
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.615
CF15_04775
NUDIX hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.587
fen
Flap structure-specific endonuclease; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair [...]
  
 
 0.575
Your Current Organism:
Pyrodictium occultum
NCBI taxonomy Id: 2309
Other names: DSM 2709, JCM 9393, NBRC 100438, P. occultum, strain PL-19
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