STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CF15_08035Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (457 aa)    
Predicted Functional Partners:
CF15_01095
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.925
guaA
GMP synthetase; Catalyzes the synthesis of GMP from XMP.
    
 0.895
CF15_01750
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.532
CF15_08415
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.532
CF15_08040
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.510
CF15_08045
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.510
CF15_06670
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.440
CF15_00155
Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
 
  
  0.439
Your Current Organism:
Pyrodictium occultum
NCBI taxonomy Id: 2309
Other names: DSM 2709, JCM 9393, NBRC 100438, P. occultum, strain PL-19
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