CVT26_002682 protein (Gymnopilus dilepis) - STRING interaction network

Nodes:

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

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[Homology]

Score

CVT26_002682

Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (275 aa)

Predicted Functional Partners:

CVT26_012523

0.594

CVT26_000836

0.573

CVT26_002057

0.564

CVT26_007003

0.564

CVT26_000534

0.443

CVT26_007094

0.443

CVT26_002526

0.443

CVT26_012732

0.443

CVT26_013685

0.440

CVT26_014395

0.435

Your Current Organism:

Gymnopilus dilepis

NCBI taxonomy Id: 231916
Other names: Agaricus dilepis, G. dilepis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CVT26_000534	CVT26_000836	A0A409VH83	A0A409YLD9	Uncharacterized protein.	Uncharacterized protein.	0.432
CVT26_000534	CVT26_002057	A0A409VH83	A0A409VBX8	Uncharacterized protein.	SURF1-like protein; Probably involved in the biogenesis of the COX complex. Belongs to the SURF1 family.	0.564
CVT26_000534	CVT26_002682	A0A409VH83	A0A409VCF6	Uncharacterized protein.	Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family.	0.443
CVT26_000534	CVT26_007003	A0A409VH83	A0A409W040	Uncharacterized protein.	Plug_translocon domain-containing protein; Belongs to the SecY/SEC61-alpha family.	0.564
CVT26_000836	CVT26_000534	A0A409YLD9	A0A409VH83	Uncharacterized protein.	Uncharacterized protein.	0.432
CVT26_000836	CVT26_002057	A0A409YLD9	A0A409VBX8	Uncharacterized protein.	SURF1-like protein; Probably involved in the biogenesis of the COX complex. Belongs to the SURF1 family.	0.959
CVT26_000836	CVT26_002526	A0A409YLD9	A0A409VSX6	Uncharacterized protein.	Uncharacterized protein.	0.432
CVT26_000836	CVT26_002682	A0A409YLD9	A0A409VCF6	Uncharacterized protein.	Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family.	0.573
CVT26_000836	CVT26_007003	A0A409YLD9	A0A409W040	Uncharacterized protein.	Plug_translocon domain-containing protein; Belongs to the SecY/SEC61-alpha family.	0.680
CVT26_000836	CVT26_007094	A0A409YLD9	A0A409VNP9	Uncharacterized protein.	Uncharacterized protein.	0.432
CVT26_000836	CVT26_012732	A0A409YLD9	A0A409WDM0	Uncharacterized protein.	Uncharacterized protein.	0.432
CVT26_000836	CVT26_013685	A0A409YLD9	A0A409YWK6	Uncharacterized protein.	Oxidored_q6 domain-containing protein; Belongs to the complex I 20 kDa subunit family.	0.952
CVT26_000836	CVT26_014395	A0A409YLD9	A0A409Y7S7	Uncharacterized protein.	NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain.	0.917
CVT26_002057	CVT26_000534	A0A409VBX8	A0A409VH83	SURF1-like protein; Probably involved in the biogenesis of the COX complex. Belongs to the SURF1 family.	Uncharacterized protein.	0.564
CVT26_002057	CVT26_000836	A0A409VBX8	A0A409YLD9	SURF1-like protein; Probably involved in the biogenesis of the COX complex. Belongs to the SURF1 family.	Uncharacterized protein.	0.959
CVT26_002057	CVT26_002526	A0A409VBX8	A0A409VSX6	SURF1-like protein; Probably involved in the biogenesis of the COX complex. Belongs to the SURF1 family.	Uncharacterized protein.	0.564
CVT26_002057	CVT26_002682	A0A409VBX8	A0A409VCF6	SURF1-like protein; Probably involved in the biogenesis of the COX complex. Belongs to the SURF1 family.	Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family.	0.564
CVT26_002057	CVT26_007003	A0A409VBX8	A0A409W040	SURF1-like protein; Probably involved in the biogenesis of the COX complex. Belongs to the SURF1 family.	Plug_translocon domain-containing protein; Belongs to the SecY/SEC61-alpha family.	0.717
CVT26_002057	CVT26_007094	A0A409VBX8	A0A409VNP9	SURF1-like protein; Probably involved in the biogenesis of the COX complex. Belongs to the SURF1 family.	Uncharacterized protein.	0.564
CVT26_002057	CVT26_012732	A0A409VBX8	A0A409WDM0	SURF1-like protein; Probably involved in the biogenesis of the COX complex. Belongs to the SURF1 family.	Uncharacterized protein.	0.564

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Network Stats

number of nodes:

11

number of edges:

13

average node degree:

2.36

avg. local clustering coefficient:

0.885

expected number of edges:

10

PPI enrichment p-value:

0.233

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0046907

Intracellular transport

5 of 521

1.35

0.95

0.0054

GO:0006886

Intracellular protein transport

4 of 319

1.46

0.92

0.0092

GO:0015031

Protein transport

5 of 823

1.15

0.74

0.0124

GO:0006606

Protein import into nucleus

2 of 40

2.06

0.74

0.0427

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0043227

Membrane-bounded organelle

11 of 7441

0.54

0.43

0.0011

GO:0043229

Intracellular organelle

11 of 7650

0.52

0.42

0.0011

GO:0005737

Cytoplasm

10 of 6797

0.53

0.41

0.0031

GO:0043231

Intracellular membrane-bounded organelle

10 of 6999

0.52

0.4

0.0033

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:3521

LAG1, DNA binding, and Protein of unknown function DUF6699

2 of 5

2.97

1.61

0.0012

CL:2008

Mixed, incl. Exportin-1/5, and Zinc finger, RanBP2-type

2 of 5

2.97

1.61

0.0012

CL:1954

Nuclear pore

3 of 32

2.34

1.58

0.0011

CL:15982

Mostly uncharacterized, incl. Serine-type endopeptidase activity, and Multifunctional anion exchangers

3 of 145

1.68

1.17

0.0035

CL:16106

Mixed, incl. Multifunctional anion exchangers, and Tyrosine/serine-protein phosphatase IphP-type

2 of 34

2.14

1.1

0.0085

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-68875

Mitotic Prophase

3 of 53

2.12

1.62

0.00076

MAP-68886

M Phase

4 of 175

1.72

1.47

0.00070

MAP-2980766

Nuclear Envelope Breakdown

2 of 26

2.25

0.92

0.0198

MAP-69278

Cell Cycle, Mitotic

4 of 630

1.17

0.66

0.0253

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR040159

Suppressor of hairless-like

2 of 2

3.37

1.39

0.0032

IPR037095

RBP-J/Cbf11, DNA binding domain superfamily

2 of 2

3.37

1.39

0.0032

IPR036358

Beta-trefoil domain superfamily

2 of 2

3.37

1.39

0.0032

IPR015351

RBP-J/Cbf11/Cbf12, DNA binding

2 of 2

3.37

1.39

0.0032

IPR015350

Beta-trefoil DNA-binding domain

2 of 2

3.37

1.39

0.0032

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM01268

Beta-trefoil DNA-binding domain

2 of 2

3.37

1.93

0.00034

SM01267

LAG1, DNA binding

2 of 2

3.37

1.93

0.00034

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