node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CVT26_000084 | CVT26_000876 | A0A409VGN9 | A0A409YLH5 | Guanylate kinase-like domain-containing protein. | dUTPase domain-containing protein. | 0.599 |
CVT26_000084 | CVT26_001745 | A0A409VGN9 | A0A409WB19 | Guanylate kinase-like domain-containing protein. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 0.493 |
CVT26_000084 | CVT26_007408 | A0A409VGN9 | A0A409VN31 | Guanylate kinase-like domain-containing protein. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | 0.848 |
CVT26_000084 | CVT26_011049 | A0A409VGN9 | A0A409VIW3 | Guanylate kinase-like domain-containing protein. | Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family. | 0.943 |
CVT26_000084 | CVT26_013843 | A0A409VGN9 | A0A409VVW0 | Guanylate kinase-like domain-containing protein. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.958 |
CVT26_000084 | CVT26_014270 | A0A409VGN9 | A0A409VXM6 | Guanylate kinase-like domain-containing protein. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.930 |
CVT26_000084 | CVT26_014452 | A0A409VGN9 | A0A409VV88 | Guanylate kinase-like domain-containing protein. | Uncharacterized protein. | 0.960 |
CVT26_000875 | CVT26_001745 | A0A409YLC7 | A0A409WB19 | GTP_cyclohydroI domain-containing protein. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 0.545 |
CVT26_000875 | CVT26_007408 | A0A409YLC7 | A0A409VN31 | GTP_cyclohydroI domain-containing protein. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | 0.488 |
CVT26_000875 | CVT26_013843 | A0A409YLC7 | A0A409VVW0 | GTP_cyclohydroI domain-containing protein. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.965 |
CVT26_000875 | CVT26_014270 | A0A409YLC7 | A0A409VXM6 | GTP_cyclohydroI domain-containing protein. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.892 |
CVT26_000876 | CVT26_000084 | A0A409YLH5 | A0A409VGN9 | dUTPase domain-containing protein. | Guanylate kinase-like domain-containing protein. | 0.599 |
CVT26_000876 | CVT26_013843 | A0A409YLH5 | A0A409VVW0 | dUTPase domain-containing protein. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.959 |
CVT26_001745 | CVT26_000084 | A0A409WB19 | A0A409VGN9 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Guanylate kinase-like domain-containing protein. | 0.493 |
CVT26_001745 | CVT26_000875 | A0A409WB19 | A0A409YLC7 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | GTP_cyclohydroI domain-containing protein. | 0.545 |
CVT26_001745 | CVT26_007408 | A0A409WB19 | A0A409VN31 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | 0.994 |
CVT26_001745 | CVT26_011049 | A0A409WB19 | A0A409VIW3 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family. | 0.916 |
CVT26_001745 | CVT26_013036 | A0A409WB19 | A0A409Y4B9 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | MGS domain-containing protein. | 0.987 |
CVT26_001745 | CVT26_013843 | A0A409WB19 | A0A409VVW0 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.975 |
CVT26_001745 | CVT26_013962 | A0A409WB19 | A0A409WUZ5 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | A_deaminase domain-containing protein. | 0.956 |