STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CVT26_014627Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (2423 aa)    
Predicted Functional Partners:
CVT26_003417
Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily.
   
0.997
CVT26_015534
Uncharacterized protein.
   
 0.996
CVT26_012661
Protein kinase domain-containing protein.
    
 0.989
CVT26_013906
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
    
 0.987
CVT26_011200
Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.
    
 0.985
CVT26_014029
Uncharacterized protein.
    
 0.985
CVT26_015108
BRCT domain-containing protein.
    
 0.985
CVT26_014667
Uncharacterized protein.
   
 0.977
CVT26_013709
Uncharacterized protein.
    
 0.974
CVT26_009618
Telomere_reg-2 domain-containing protein.
    
 0.971
Your Current Organism:
Gymnopilus dilepis
NCBI taxonomy Id: 231916
Other names: Agaricus dilepis, G. dilepis
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.