CVT26_007934 protein (Gymnopilus dilepis) - STRING interaction network

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second shell of interactors

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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Gene Fusion

Cooccurrence

Coexpression

Experiments

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[Homology]

Score

CVT26_007934

Uncharacterized protein. (448 aa)

Predicted Functional Partners:

CVT26_010916

0.999

CVT26_014599

0.999

CVT26_014263

0.999

CVT26_006957

0.999

CVT26_015810

0.999

CVT26_008566

0.999

CVT26_003206

0.999

CVT26_000089

0.998

CVT26_013928

0.998

CVT26_006615

0.998

Your Current Organism:

Gymnopilus dilepis

NCBI taxonomy Id: 231916
Other names: Agaricus dilepis, G. dilepis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CVT26_000089	CVT26_003206	A0A409VGQ4	A0A409Y581	AAA domain-containing protein.	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	0.999
CVT26_000089	CVT26_006615	A0A409VGQ4	A0A409Y349	AAA domain-containing protein.	DNA helicase; Belongs to the MCM family.	0.999
CVT26_000089	CVT26_006957	A0A409VGQ4	A0A409W6A8	AAA domain-containing protein.	Uncharacterized protein.	0.999
CVT26_000089	CVT26_007934	A0A409VGQ4	A0A409W7Q4	AAA domain-containing protein.	Uncharacterized protein.	0.998
CVT26_000089	CVT26_008566	A0A409VGQ4	A0A409XXU7	AAA domain-containing protein.	ORC_WH_C domain-containing protein.	0.999
CVT26_000089	CVT26_010916	A0A409VGQ4	A0A409VIP9	AAA domain-containing protein.	DNA helicase; Belongs to the MCM family.	0.998
CVT26_000089	CVT26_013928	A0A409VGQ4	A0A409VVZ0	AAA domain-containing protein.	DNA helicase; Belongs to the MCM family.	0.999
CVT26_000089	CVT26_014263	A0A409VGQ4	A0A409VXJ6	AAA domain-containing protein.	DNA helicase; Belongs to the MCM family.	0.999
CVT26_000089	CVT26_014599	A0A409VGQ4	A0A409VVQ7	AAA domain-containing protein.	DNA helicase.	0.999
CVT26_000089	CVT26_015810	A0A409VGQ4	A0A409WHK0	AAA domain-containing protein.	Uncharacterized protein.	0.999
CVT26_003206	CVT26_000089	A0A409Y581	A0A409VGQ4	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	AAA domain-containing protein.	0.999
CVT26_003206	CVT26_006615	A0A409Y581	A0A409Y349	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	DNA helicase; Belongs to the MCM family.	0.999
CVT26_003206	CVT26_006957	A0A409Y581	A0A409W6A8	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	Uncharacterized protein.	0.999
CVT26_003206	CVT26_007934	A0A409Y581	A0A409W7Q4	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	Uncharacterized protein.	0.999
CVT26_003206	CVT26_008566	A0A409Y581	A0A409XXU7	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	ORC_WH_C domain-containing protein.	0.999
CVT26_003206	CVT26_010916	A0A409Y581	A0A409VIP9	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	DNA helicase; Belongs to the MCM family.	0.998
CVT26_003206	CVT26_013928	A0A409Y581	A0A409VVZ0	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	DNA helicase; Belongs to the MCM family.	0.998
CVT26_003206	CVT26_014263	A0A409Y581	A0A409VXJ6	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	DNA helicase; Belongs to the MCM family.	0.998
CVT26_003206	CVT26_014599	A0A409Y581	A0A409VVQ7	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	DNA helicase.	0.998
CVT26_003206	CVT26_015810	A0A409Y581	A0A409WHK0	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.	Uncharacterized protein.	0.999

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Network Stats

number of nodes:

11

number of edges:

54

average node degree:

9.82

avg. local clustering coefficient:

0.982

expected number of edges:

24

PPI enrichment p-value:

9.83e-08

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006325

Chromatin organization

5 of 188

1.32

0.88

0.0078

GO:0006357

Regulation of transcription by RNA polymerase II

5 of 313

1.1

0.69

0.0149

GO:0016570

Histone modification

3 of 83

1.45

0.68

0.0371

GO:0006355

Regulation of transcription, DNA-templated

6 of 450

1.02

0.65

0.0137

GO:0006338

Chromatin remodeling

3 of 91

1.41

0.64

0.0450

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0004402

Histone acetyltransferase activity

3 of 15

2.19

1.45

0.0018

GO:0140064

Peptide crotonyltransferase activity

2 of 3

2.72

1.25

0.0054

GO:0010484

H3 histone acetyltransferase activity

2 of 3

2.72

1.25

0.0054

GO:0030527

Structural constituent of chromatin

2 of 10

2.19

0.97

0.0157

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0000786

Nucleosome

2 of 13

2.08

0.74

0.0427

GO:0005694

Chromosome

5 of 319

1.09

0.71

0.0117

GO:0000124

SAGA complex

2 of 16

1.99

0.71

0.0465

GO:0005634

Nucleus

10 of 2090

0.57

0.42

0.0053

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-9018519

Estrogen-dependent gene expression

6 of 37

2.1

3.83

4.52e-09

MAP-8939211

ESR-mediated signaling

6 of 43

2.04

3.7

5.17e-09

MAP-9006931

Signaling by Nuclear Receptors

6 of 95

1.69

2.54

3.04e-07

MAP-2299718

Condensation of Prophase Chromosomes

2 of 7

2.35

1.09

0.0097

MAP-162582

Signal Transduction

8 of 603

1.01

1.05

1.95e-05

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0544

Nucleosome core

2 of 6

2.41

1.26

0.0048

KW-0539

Nucleus

5 of 289

1.13

0.84

0.0041

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR039355

Transcription factor GATA

2 of 2

2.89

0.91

0.0224

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00401

Zinc finger binding to DNA consensus sequence [AT]GATA[AG]

2 of 5

2.49

1.11

0.0095

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