CVT26_005853 protein (Gymnopilus dilepis) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

CVT26_005853

Uncharacterized protein. (1071 aa)

Predicted Functional Partners:

CVT26_007373

0.712

CVT26_002143

0.665

CVT26_009282

0.635

CVT26_009400

0.595

CVT26_000017

0.523

CVT26_015534

0.519

CVT26_009401

0.516

CVT26_007121

0.516

CVT26_010332

0.516

CVT26_001670

0.516

Your Current Organism:

Gymnopilus dilepis

NCBI taxonomy Id: 231916
Other names: Agaricus dilepis, G. dilepis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CVT26_000017	CVT26_002143	A0A409VGJ8	A0A409VBR1	Uncharacterized protein.	Carrier domain-containing protein.	0.921
CVT26_000017	CVT26_005853	A0A409VGJ8	A0A409WBW0	Uncharacterized protein.	Uncharacterized protein.	0.523
CVT26_000017	CVT26_009282	A0A409VGJ8	A0A409YAI2	Uncharacterized protein.	Tryptophan synthase.	0.870
CVT26_001670	CVT26_002143	A0A409WB83	A0A409VBR1	NAD_binding_4 domain-containing protein.	Carrier domain-containing protein.	0.921
CVT26_001670	CVT26_005853	A0A409WB83	A0A409WBW0	NAD_binding_4 domain-containing protein.	Uncharacterized protein.	0.516
CVT26_001670	CVT26_009282	A0A409WB83	A0A409YAI2	NAD_binding_4 domain-containing protein.	Tryptophan synthase.	0.870
CVT26_002143	CVT26_000017	A0A409VBR1	A0A409VGJ8	Carrier domain-containing protein.	Uncharacterized protein.	0.921
CVT26_002143	CVT26_001670	A0A409VBR1	A0A409WB83	Carrier domain-containing protein.	NAD_binding_4 domain-containing protein.	0.921
CVT26_002143	CVT26_005853	A0A409VBR1	A0A409WBW0	Carrier domain-containing protein.	Uncharacterized protein.	0.665
CVT26_002143	CVT26_007121	A0A409VBR1	A0A409W1B7	Carrier domain-containing protein.	Uncharacterized protein.	0.921
CVT26_002143	CVT26_007373	A0A409VBR1	A0A409VP24	Carrier domain-containing protein.	Uncharacterized protein.	0.538
CVT26_002143	CVT26_009400	A0A409VBR1	A0A409VKA5	Carrier domain-containing protein.	Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family.	0.408
CVT26_002143	CVT26_009401	A0A409VBR1	A0A409VK96	Carrier domain-containing protein.	Uncharacterized protein.	0.921
CVT26_002143	CVT26_010332	A0A409VBR1	A0A409W4Q5	Carrier domain-containing protein.	Uncharacterized protein.	0.921
CVT26_002143	CVT26_015534	A0A409VBR1	A0A409YD55	Carrier domain-containing protein.	Uncharacterized protein.	0.693
CVT26_005853	CVT26_000017	A0A409WBW0	A0A409VGJ8	Uncharacterized protein.	Uncharacterized protein.	0.523
CVT26_005853	CVT26_001670	A0A409WBW0	A0A409WB83	Uncharacterized protein.	NAD_binding_4 domain-containing protein.	0.516
CVT26_005853	CVT26_002143	A0A409WBW0	A0A409VBR1	Uncharacterized protein.	Carrier domain-containing protein.	0.665
CVT26_005853	CVT26_007121	A0A409WBW0	A0A409W1B7	Uncharacterized protein.	Uncharacterized protein.	0.516
CVT26_005853	CVT26_007373	A0A409WBW0	A0A409VP24	Uncharacterized protein.	Uncharacterized protein.	0.712

page 1 of 3

Network Stats

number of nodes:

11

number of edges:

39

average node degree:

7.09

avg. local clustering coefficient:

0.95

expected number of edges:

25

PPI enrichment p-value:

0.00477

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006412

Translation

7 of 98

1.44

1.91

1.55e-06

GO:0010467

Gene expression

8 of 203

1.18

1.43

1.55e-06

GO:0009059

Macromolecule biosynthetic process

8 of 233

1.12

1.3

2.53e-06

GO:0044271

Cellular nitrogen compound biosynthetic process

8 of 314

0.99

1.02

1.67e-05

GO:0009987

Cellular process

10 of 1616

0.37

0.27

0.0284

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003735

Structural constituent of ribosome

6 of 54

1.63

2.24

1.49e-06

GO:0019843

rRNA binding

4 of 40

1.58

1.42

0.00057

GO:0000049

tRNA binding

3 of 20

1.76

1.3

0.0020

GO:0003723

RNA binding

5 of 98

1.29

1.17

0.00057

GO:0005525

GTP binding

3 of 32

1.55

1.02

0.0062

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005840

Ribosome

6 of 62

1.57

2.23

6.25e-07

GO:0044391

Ribosomal subunit

3 of 13

1.94

1.91

0.00012

GO:0015935

Small ribosomal subunit

2 of 6

2.1

1.39

0.0022

GO:0032991

Protein-containing complex

4 of 119

1.11

0.88

0.0022

GO:0005622

Intracellular anatomical structure

8 of 885

0.54

0.41

0.0036

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:300

Ribosome

8 of 61

1.7

3.23

4.70e-10

CL:304

Ribosome

7 of 52

1.71

3.07

3.34e-09

CL:306

rRNA-binding

4 of 27

1.75

1.93

4.70e-05

CL:366

Ribosome

3 of 13

1.94

1.67

0.00042

CL:368

Structural constituent of ribosome

2 of 6

2.1

1.1

0.0082

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

sgn03010

Ribosome

6 of 55

1.62

2.4

3.23e-07

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0009507

Chloroplast

3 of 25

1.66

0.98

0.0100

GOCC:0005840

Ribosome

3 of 39

1.47

0.91

0.0100

GOCC:0043229

Intracellular organelle

6 of 288

0.9

0.61

0.0100

GOCC:0005622

Intracellular

9 of 959

0.55

0.39

0.0100

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0689

Ribosomal protein

6 of 58

1.6

2.26

7.88e-07

KW-0699

rRNA-binding

3 of 37

1.49

0.96

0.0077

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF03144

Elongation factor Tu domain 2

2 of 4

2.28

0.78

0.0376

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR005225

Small GTP-binding protein domain

3 of 10

2.06

1.25

0.0041

IPR035647

EF-G domain III/V-like

2 of 4

2.28

0.8

0.0340

IPR031157

Tr-type G domain, conserved site

2 of 4

2.28

0.8

0.0340

IPR004161

Translation elongation factor EFTu-like, domain 2

2 of 4

2.28

0.8

0.0340

IPR000640

Elongation factor EFG, domain V-like

2 of 3

2.41

0.8

0.0340

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00838

Elongation factor G C-terminus

2 of 3

2.41

1.2

0.0061

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