| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SIN74302.1 | SIN78918.1 | SAMN05443544_0739 | SAMN05443544_1173 | Glutamate synthase (NADH) large subunit. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.661 |
| SIN74302.1 | SIO21071.1 | SAMN05443544_0739 | SAMN05443544_3333 | Glutamate synthase (NADH) large subunit. | Succinyldiaminopimelate aminotransferase apoenzyme. | 0.949 |
| SIN74302.1 | SIO21499.1 | SAMN05443544_0739 | SAMN05443544_3365 | Glutamate synthase (NADH) large subunit. | Phenazine biosynthesis protein phzE. | 0.899 |
| SIN74302.1 | dapF | SAMN05443544_0739 | SAMN05443544_2937 | Glutamate synthase (NADH) large subunit. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.960 |
| SIN74302.1 | gcvP | SAMN05443544_0739 | SAMN05443544_3351 | Glutamate synthase (NADH) large subunit. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.970 |
| SIN78918.1 | SIN74302.1 | SAMN05443544_1173 | SAMN05443544_0739 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Glutamate synthase (NADH) large subunit. | 0.661 |
| SIN78918.1 | SIO21071.1 | SAMN05443544_1173 | SAMN05443544_3333 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Succinyldiaminopimelate aminotransferase apoenzyme. | 0.776 |
| SIN78918.1 | dapF | SAMN05443544_1173 | SAMN05443544_2937 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.465 |
| SIN78918.1 | gcvP | SAMN05443544_1173 | SAMN05443544_3351 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.922 |
| SIO20985.1 | SIO21071.1 | SAMN05443544_3326 | SAMN05443544_3333 | Succinyldiaminopimelate desuccinylase. | Succinyldiaminopimelate aminotransferase apoenzyme. | 0.973 |
| SIO20985.1 | dapB | SAMN05443544_3326 | SAMN05443544_2968 | Succinyldiaminopimelate desuccinylase. | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | 0.737 |
| SIO20985.1 | dapD | SAMN05443544_3326 | SAMN05443544_3330 | Succinyldiaminopimelate desuccinylase. | 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA. | 0.880 |
| SIO20985.1 | dapF | SAMN05443544_3326 | SAMN05443544_2937 | Succinyldiaminopimelate desuccinylase. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.987 |
| SIO20985.1 | lysA | SAMN05443544_3326 | SAMN05443544_3158 | Succinyldiaminopimelate desuccinylase. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.770 |
| SIO21071.1 | SIN74302.1 | SAMN05443544_3333 | SAMN05443544_0739 | Succinyldiaminopimelate aminotransferase apoenzyme. | Glutamate synthase (NADH) large subunit. | 0.949 |
| SIO21071.1 | SIN78918.1 | SAMN05443544_3333 | SAMN05443544_1173 | Succinyldiaminopimelate aminotransferase apoenzyme. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.776 |
| SIO21071.1 | SIO20985.1 | SAMN05443544_3333 | SAMN05443544_3326 | Succinyldiaminopimelate aminotransferase apoenzyme. | Succinyldiaminopimelate desuccinylase. | 0.973 |
| SIO21071.1 | SIO21085.1 | SAMN05443544_3333 | SAMN05443544_3334 | Succinyldiaminopimelate aminotransferase apoenzyme. | NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. | 0.870 |
| SIO21071.1 | SIO21499.1 | SAMN05443544_3333 | SAMN05443544_3365 | Succinyldiaminopimelate aminotransferase apoenzyme. | Phenazine biosynthesis protein phzE. | 0.735 |
| SIO21071.1 | dapB | SAMN05443544_3333 | SAMN05443544_2968 | Succinyldiaminopimelate aminotransferase apoenzyme. | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | 0.891 |