node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
gcvH1 | gcvH2 | TKV_c00910 | TKV_c02420 | Glycine cleavage system H protein GcvH; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Glycine cleavage system H protein GcvH; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.901 |
gcvH1 | gcvH3 | TKV_c00910 | TKV_c19100 | Glycine cleavage system H protein GcvH; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Glycine cleavage system H protein GcvH. | 0.912 |
gcvH1 | gcvH4 | TKV_c00910 | TKV_c19810 | Glycine cleavage system H protein GcvH; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Glycine cleavage system H protein GcvH; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.905 |
gcvH1 | gcvPA | TKV_c00910 | TKV_c02410 | Glycine cleavage system H protein GcvH; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Glycine dehydrogenase (decarboxylating) subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | 0.989 |
gcvH1 | gcvPB | TKV_c00910 | TKV_c02400 | Glycine cleavage system H protein GcvH; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Glycine dehydrogenase (decarboxylating) subunit 2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. | 0.992 |
gcvH1 | gcvT | TKV_c00910 | TKV_c02430 | Glycine cleavage system H protein GcvH; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Aminomethyltransferase GcvT; The glycine cleavage system catalyzes the degradation of glycine. | 0.997 |
gcvH1 | glyA | TKV_c00910 | TKV_c18380 | Glycine cleavage system H protein GcvH; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Serine hydroxymethyltransferase GlyA; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.960 |
gcvH1 | lpdA1 | TKV_c00910 | TKV_c00900 | Glycine cleavage system H protein GcvH; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Dihydrolipoyl dehydrogenase LpdA. | 0.973 |
gcvH1 | pdhD | TKV_c00910 | TKV_c15680 | Glycine cleavage system H protein GcvH; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Dihydrolipoyl dehydrogenase PdhD. | 0.944 |
gcvH2 | gcvH1 | TKV_c02420 | TKV_c00910 | Glycine cleavage system H protein GcvH; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Glycine cleavage system H protein GcvH; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.901 |
gcvH2 | gcvH3 | TKV_c02420 | TKV_c19100 | Glycine cleavage system H protein GcvH; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Glycine cleavage system H protein GcvH. | 0.913 |
gcvH2 | gcvH4 | TKV_c02420 | TKV_c19810 | Glycine cleavage system H protein GcvH; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Glycine cleavage system H protein GcvH; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.904 |
gcvH2 | gcvPA | TKV_c02420 | TKV_c02410 | Glycine cleavage system H protein GcvH; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Glycine dehydrogenase (decarboxylating) subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | 0.997 |
gcvH2 | gcvPB | TKV_c02420 | TKV_c02400 | Glycine cleavage system H protein GcvH; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Glycine dehydrogenase (decarboxylating) subunit 2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. | 0.998 |
gcvH2 | gcvT | TKV_c02420 | TKV_c02430 | Glycine cleavage system H protein GcvH; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Aminomethyltransferase GcvT; The glycine cleavage system catalyzes the degradation of glycine. | 0.999 |
gcvH2 | glyA | TKV_c02420 | TKV_c18380 | Glycine cleavage system H protein GcvH; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Serine hydroxymethyltransferase GlyA; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.963 |
gcvH2 | lpdA1 | TKV_c02420 | TKV_c00900 | Glycine cleavage system H protein GcvH; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Dihydrolipoyl dehydrogenase LpdA. | 0.944 |
gcvH2 | pdhD | TKV_c02420 | TKV_c15680 | Glycine cleavage system H protein GcvH; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Dihydrolipoyl dehydrogenase PdhD. | 0.942 |
gcvH3 | gcvH1 | TKV_c19100 | TKV_c00910 | Glycine cleavage system H protein GcvH. | Glycine cleavage system H protein GcvH; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.912 |
gcvH3 | gcvH2 | TKV_c19100 | TKV_c02420 | Glycine cleavage system H protein GcvH. | Glycine cleavage system H protein GcvH; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.913 |