node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AIS51737.1 | motA | TKV_c05390 | TKV_c05400 | ABC transporter ATPase component. | Motility protein A. | 0.550 |
AIS51737.1 | rex | TKV_c05390 | TKV_c05420 | ABC transporter ATPase component. | Redox-sensing transcriptional repressor Rex; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. | 0.497 |
AIS51737.1 | rpsP | TKV_c05390 | TKV_c13770 | ABC transporter ATPase component. | 30S ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family. | 0.839 |
codY | rex | TKV_c13620 | TKV_c05420 | GTP-sensing transcriptional pleiotropic repressor CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; Belongs to the CodY family. | Redox-sensing transcriptional repressor Rex; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. | 0.628 |
echA8 | rex | TKV_c00330 | TKV_c05420 | enoyl-CoA hydratase EchA8. | Redox-sensing transcriptional repressor Rex; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. | 0.527 |
echA8 | rpsP | TKV_c00330 | TKV_c13770 | enoyl-CoA hydratase EchA8. | 30S ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family. | 0.833 |
gyrA | rex | TKV_c00100 | TKV_c05420 | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | Redox-sensing transcriptional repressor Rex; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. | 0.620 |
gyrA | rnpA | TKV_c00100 | TKV_c24800 | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | Ribonuclease P protein component RnpA; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 0.658 |
hydA1 | rex | TKV_c19580 | TKV_c05420 | Electron bifurcating hydrogenase subunit HydA1. | Redox-sensing transcriptional repressor Rex; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. | 0.566 |
ldh1 | pyrE | TKV_c02310 | TKV_c14380 | L-lactate dehydrogenase Ldh; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. | Orotate phosphoribosyltransferase PyrE; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.555 |
ldh1 | rex | TKV_c02310 | TKV_c05420 | L-lactate dehydrogenase Ldh; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. | Redox-sensing transcriptional repressor Rex; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. | 0.682 |
motA | AIS51737.1 | TKV_c05400 | TKV_c05390 | Motility protein A. | ABC transporter ATPase component. | 0.550 |
motA | rex | TKV_c05400 | TKV_c05420 | Motility protein A. | Redox-sensing transcriptional repressor Rex; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. | 0.527 |
pyrE | ldh1 | TKV_c14380 | TKV_c02310 | Orotate phosphoribosyltransferase PyrE; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | L-lactate dehydrogenase Ldh; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. | 0.555 |
pyrE | rex | TKV_c14380 | TKV_c05420 | Orotate phosphoribosyltransferase PyrE; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | Redox-sensing transcriptional repressor Rex; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. | 0.619 |
rex | AIS51737.1 | TKV_c05420 | TKV_c05390 | Redox-sensing transcriptional repressor Rex; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. | ABC transporter ATPase component. | 0.497 |
rex | codY | TKV_c05420 | TKV_c13620 | Redox-sensing transcriptional repressor Rex; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. | GTP-sensing transcriptional pleiotropic repressor CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; Belongs to the CodY family. | 0.628 |
rex | echA8 | TKV_c05420 | TKV_c00330 | Redox-sensing transcriptional repressor Rex; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. | enoyl-CoA hydratase EchA8. | 0.527 |
rex | gyrA | TKV_c05420 | TKV_c00100 | Redox-sensing transcriptional repressor Rex; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.620 |
rex | hydA1 | TKV_c05420 | TKV_c19580 | Redox-sensing transcriptional repressor Rex; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. | Electron bifurcating hydrogenase subunit HydA1. | 0.566 |