STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AIS52272.1Vitamin B12 dependent methionine synthase. (824 aa)    
Predicted Functional Partners:
acsC
Corrinoid iron sulfur protein subunit alpha.
 
   0.882
acsD
Corrinoid iron sulfur protein subunit beta.
 
 
   0.880
AIS52273.1
ABC transporter, ATPase, putative.
       0.678
acsB
CO dehydrogenase/acetyl-CoA synthase complex, beta subunit.
 
     0.575
mdeA
Methionine gamma-lyase MdeA.
  
  
  0.565
metV
5,10-methylene-tetrahydrofolate reductase subunit MetV.
 
   
 0.543
metK
S-adenosylmethionine synthase MetK; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
     
  0.499
luxS
S-ribosylhomocysteine lyase LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.
     
  0.499
cooC1
CO dehydrogenase nickel-insertion accessory protein CooC.
 
     0.428
metH
Methionine synthase MetH.
   
 
 0.409
Your Current Organism:
Thermoanaerobacter kivui
NCBI taxonomy Id: 2325
Other names: ATCC 33488, Acetogenium kivuense, Acetogenium kivui, DSM 2030, T. kivui, Thermoanaerobacter kivuense
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.