node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
aroF2 | trpA | TKV_c14830 | TKV_c14840 | Phospho-2-dehydro-3-deoxyheptonate aldolase AroF. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.801 |
aroF2 | trpB | TKV_c14830 | TKV_c14850 | Phospho-2-dehydro-3-deoxyheptonate aldolase AroF. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.790 |
aroF2 | trpC | TKV_c14830 | TKV_c14870 | Phospho-2-dehydro-3-deoxyheptonate aldolase AroF. | Indole-3-glycerol phosphate synthase TrpC; Belongs to the TrpC family. | 0.800 |
aroF2 | trpD | TKV_c14830 | TKV_c14880 | Phospho-2-dehydro-3-deoxyheptonate aldolase AroF. | Anthranilate phosphoribosyltransferase TrpD; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.796 |
aroF2 | trpE1 | TKV_c14830 | TKV_c14900 | Phospho-2-dehydro-3-deoxyheptonate aldolase AroF. | Anthranilate synthase component 1; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.783 |
aroF2 | trpF | TKV_c14830 | TKV_c14860 | Phospho-2-dehydro-3-deoxyheptonate aldolase AroF. | N-(5'-phosphoribosyl)anthranilate isomerase TrpF; Belongs to the TrpF family. | 0.796 |
aroF2 | trpGD | TKV_c14830 | TKV_c14890 | Phospho-2-dehydro-3-deoxyheptonate aldolase AroF. | Bifunctional protein TrpGD. | 0.781 |
hisI | pabA | TKV_c18410 | TKV_c19640 | Histidine biosynthesis bifunctional protein HisIE; In the N-terminal section; belongs to the PRA-CH family. | Aminodeoxychorismate synthase component 2. | 0.504 |
hisI | trpA | TKV_c18410 | TKV_c14840 | Histidine biosynthesis bifunctional protein HisIE; In the N-terminal section; belongs to the PRA-CH family. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.717 |
hisI | trpB | TKV_c18410 | TKV_c14850 | Histidine biosynthesis bifunctional protein HisIE; In the N-terminal section; belongs to the PRA-CH family. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.617 |
hisI | trpC | TKV_c18410 | TKV_c14870 | Histidine biosynthesis bifunctional protein HisIE; In the N-terminal section; belongs to the PRA-CH family. | Indole-3-glycerol phosphate synthase TrpC; Belongs to the TrpC family. | 0.677 |
hisI | trpD | TKV_c18410 | TKV_c14880 | Histidine biosynthesis bifunctional protein HisIE; In the N-terminal section; belongs to the PRA-CH family. | Anthranilate phosphoribosyltransferase TrpD; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.712 |
hisI | trpE1 | TKV_c18410 | TKV_c14900 | Histidine biosynthesis bifunctional protein HisIE; In the N-terminal section; belongs to the PRA-CH family. | Anthranilate synthase component 1; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.728 |
hisI | trpE2 | TKV_c18410 | TKV_c19630 | Histidine biosynthesis bifunctional protein HisIE; In the N-terminal section; belongs to the PRA-CH family. | Anthranilate synthase component 1. | 0.499 |
hisI | trpF | TKV_c18410 | TKV_c14860 | Histidine biosynthesis bifunctional protein HisIE; In the N-terminal section; belongs to the PRA-CH family. | N-(5'-phosphoribosyl)anthranilate isomerase TrpF; Belongs to the TrpF family. | 0.829 |
hisI | trpGD | TKV_c18410 | TKV_c14890 | Histidine biosynthesis bifunctional protein HisIE; In the N-terminal section; belongs to the PRA-CH family. | Bifunctional protein TrpGD. | 0.504 |
pabA | hisI | TKV_c19640 | TKV_c18410 | Aminodeoxychorismate synthase component 2. | Histidine biosynthesis bifunctional protein HisIE; In the N-terminal section; belongs to the PRA-CH family. | 0.504 |
pabA | trpA | TKV_c19640 | TKV_c14840 | Aminodeoxychorismate synthase component 2. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.903 |
pabA | trpB | TKV_c19640 | TKV_c14850 | Aminodeoxychorismate synthase component 2. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.767 |
pabA | trpC | TKV_c19640 | TKV_c14870 | Aminodeoxychorismate synthase component 2. | Indole-3-glycerol phosphate synthase TrpC; Belongs to the TrpC family. | 0.991 |