STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AIS52836.1AIPM/hcit synthase family; Belongs to the alpha-IPM synthase/homocitrate synthase family. (520 aa)    
Predicted Functional Partners:
leuD
3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily.
  
 
 0.993
leuC
3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
 
 
 0.990
ilvE
Putative branched-chain-amino-acid aminotransferase IlvE; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
 
 0.977
ilvD
Dihydroxy-acid dehydratase IlvD; Belongs to the IlvD/Edd family.
  
 
 0.971
leuB
3-isopropylmalate dehydrogenase LeuB; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
 
 0.948
nifJ1
Pyruvate-flavodoxin oxidoreductase NifJ; Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
  
 
 0.948
leuA1
2-isopropylmalate synthase 1; Belongs to the alpha-IPM synthase/homocitrate synthase family.
 
  
 
0.940
nifJ2
Pyruvate-flavodoxin oxidoreductase NifJ; Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
  
 
 0.939
leuA2
2-isopropylmalate synthase 2; Belongs to the alpha-IPM synthase/homocitrate synthase family.
  
  
 
0.921
ilvH
Acetolactate synthase small subunit.
  
 
 0.919
Your Current Organism:
Thermoanaerobacter kivui
NCBI taxonomy Id: 2325
Other names: ATCC 33488, Acetogenium kivuense, Acetogenium kivui, DSM 2030, T. kivui, Thermoanaerobacter kivuense
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.