STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ldh2Leucine dehydrogenase Ldh; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (355 aa)    
Predicted Functional Partners:
buk2
Butyrate kinase 2; Belongs to the acetokinase family.
  
  
 0.931
ilvD
Dihydroxy-acid dehydratase IlvD; Belongs to the IlvD/Edd family.
   
 
 0.919
ilvE
Putative branched-chain-amino-acid aminotransferase IlvE; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
  
 
 0.917
leuA1
2-isopropylmalate synthase 1; Belongs to the alpha-IPM synthase/homocitrate synthase family.
   
 
 0.908
AIS52836.1
AIPM/hcit synthase family; Belongs to the alpha-IPM synthase/homocitrate synthase family.
   
 
 0.908
buk1
Butyrate kinase 1; Belongs to the acetokinase family.
  
  
 0.893
ptb2
Phosphate butyryltransferase Ptb.
  
  
 0.877
cobB2
NAD-dependent protein deacetylase 2; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.
   
 0.819
nifJ1
Pyruvate-flavodoxin oxidoreductase NifJ; Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
  
  
 0.726
ptb1
Phosphate butyryltransferase Ptb.
  
  
 0.704
Your Current Organism:
Thermoanaerobacter kivui
NCBI taxonomy Id: 2325
Other names: ATCC 33488, Acetogenium kivuense, Acetogenium kivui, DSM 2030, T. kivui, Thermoanaerobacter kivuense
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.