STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AIS53242.16-pyruvoyltetrahydropterin/6- carboxytetrahydropterin synthase. (121 aa)    
Predicted Functional Partners:
folE
GTP cyclohydrolase 1.
  
 
 0.997
phoB1
Alkaline phosphatase 3; Belongs to the alkaline phosphatase family.
     
  0.900
queF
NADPH-dependent 7-cyano-7-deazaguanine reductase QueF; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
 
  
 0.859
AIS53570.1
cAMP-binding protein.
    
  0.840
folK
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase FolK.
     
 0.831
sul
Dihydropteroate synthase Sul; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
     
 0.818
hisI
Histidine biosynthesis bifunctional protein HisIE; In the N-terminal section; belongs to the PRA-CH family.
     
 0.667
sfsA
Sugar fermentation stimulation protein SfsA; Belongs to the SfsA family.
       0.544
cysS
cysteine--tRNA ligase CysS; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
  
 0.540
lysS
lysine--tRNA ligase LysS; Belongs to the class-II aminoacyl-tRNA synthetase family.
       0.495
Your Current Organism:
Thermoanaerobacter kivui
NCBI taxonomy Id: 2325
Other names: ATCC 33488, Acetogenium kivuense, Acetogenium kivui, DSM 2030, T. kivui, Thermoanaerobacter kivuense
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