STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dapESuccinyldiaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. (391 aa)    
Predicted Functional Partners:
Ajs_2066
Succinyldiaminopimelate aminotransferase apoenzyme; PFAM: aminotransferase, class I and II; KEGG: pol:Bpro_1997 aminotransferase, class I and II.
 
  
 0.968
dapF
Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.
    
 0.939
argD
TIGRFAM: acetylornithine and succinylornithine aminotransferases; PFAM: aminotransferase class-III; KEGG: pol:Bpro_3572 acetylornithine and succinylornithine aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
  
 
 0.922
Ajs_2070
[LSU ribosomal protein L3P]-glutamine N5-methyltransferase; KEGG: rfr:Rfer_2043 modification methylase, HemK family; TIGRFAM: modification methylase, HemK family; PFAM: putative RNA methylase; methyltransferase small; Belongs to the protein N5-glutamine methyltransferase family.
 
  
 0.917
dapD
KEGG: pol:Bpro_1996 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; TIGRFAM: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; PFAM: transferase hexapeptide repeat containing protein; Belongs to the transferase hexapeptide repeat family.
 
  
 0.846
Ajs_2071
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: pol:Bpro_1992 ABC transporter related.
   
   0.735
Ajs_2068
TIGRFAM: twitching motility protein; PFAM: type II secretion system protein E; KEGG: pol:Bpro_1995 twitching motility protein.
       0.733
argA
N-acetylglutamate synthase; TIGRFAM: amino-acid N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; aspartate/glutamate/uridylate kinase; KEGG: rfr:Rfer_2105 amino-acid N-acetyltransferase (ArgA); Belongs to the acetyltransferase family. ArgA subfamily.
  
  
 0.614
dnaQ
DNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.
 
   
 0.553
argC
N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 2 subfamily.
  
 
 0.519
Your Current Organism:
Acidovorax sp. JS42
NCBI taxonomy Id: 232721
Other names: A. sp. JS42
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.