STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ligADNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. (731 aa)    
Predicted Functional Partners:
Ajs_0311
PFAM: ATP dependent DNA ligase domain protein; ATP dependent DNA ligase; KEGG: reu:Reut_B3895 DNA ligase (ATP).
    
 0.914
Ajs_2761
PFAM: ATP dependent DNA ligase; KEGG: pol:Bpro_2416 ATP dependent DNA ligase.
    
 0.914
Ajs_2085
SMART: ZipA, C-terminal FtsZ-binding region; KEGG: rfr:Rfer_2200 hypothetical protein.
       0.857
smc
Chromosome segregation protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family.
  
  
 0.821
leuS
TIGRFAM: leucyl-tRNA synthetase; KEGG: rfr:Rfer_0758 leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
 
 
 0.821
Ajs_2082
PFAM: Patatin; KEGG: nmu:Nmul_A0164 patatin.
     
 0.800
Ajs_2084
KEGG: neu:NE2258 hypothetical protein.
       0.772
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
 
   
 0.735
Ajs_3324
PFAM: UvrD/REP helicase; KEGG: pol:Bpro_1723 UvrD/REP helicase.
 
  
 0.717
rep
UvrD/REP helicase; Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.
 
  
 0.700
Your Current Organism:
Acidovorax sp. JS42
NCBI taxonomy Id: 232721
Other names: A. sp. JS42
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