STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ajs_2126KEGG: pol:Bpro_2673 multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein. (848 aa)    
Predicted Functional Partners:
Ajs_2127
Two component transcriptional regulator, LuxR family; PFAM: regulatory protein, LuxR; response regulator receiver; Sigma-70, region 4 type 2; KEGG: pol:Bpro_2674 two component transcriptional regulator, LuxR family.
 
 
 0.964
Ajs_0647
Multi-sensor hybrid histidine kinase; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; CHASE3 domain protein; KEGG: mes:Meso_1942 multi-sensor hybrid histidine kinase.
  
 
 0.956
Ajs_0650
PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: xcb:XC_3060 two-component system regulatory protein.
 
 0.946
Ajs_1934
Signal transduction histidine kinase, nitrogen specific, NtrB; KEGG: rfr:Rfer_2766 PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein.
 
 
0.920
Ajs_0554
Integral membrane sensor hybrid histidine kinase; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; KEGG: rfr:Rfer_2038 periplasmic sensor hybrid histidine kinase.
 
 
 
 0.830
Ajs_0088
KEGG: rfr:Rfer_0458 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; GAF domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.
  
 
 0.789
folD
5,10-methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
 
    0.772
Ajs_2494
TIGRFAM: phasin family protein; KEGG: pol:Bpro_3088 phasin.
  
     0.756
Ajs_3104
KEGG: csa:Csal_1723 diguanylate cyclase with PAS/PAC sensor; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein.
  
 
 0.754
Ajs_4015
PFAM: regulatory protein, LuxR; response regulator receiver; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2; KEGG: pol:Bpro_4652 two component transcriptional regulator, LuxR family.
 
 
 0.750
Your Current Organism:
Acidovorax sp. JS42
NCBI taxonomy Id: 232721
Other names: A. sp. JS42
Server load: medium (50%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.