node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SIT70188.1 | SIT70201.1 | SAMN05216526_1256 | SAMN05216526_1259 | FKBP-type peptidyl-prolyl cis-trans isomerase SlpA. | Riboflavin kinase / FMN adenylyltransferase; Belongs to the ribF family. | 0.789 |
SIT70188.1 | ileS | SAMN05216526_1256 | SAMN05216526_1258 | FKBP-type peptidyl-prolyl cis-trans isomerase SlpA. | Isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | 0.920 |
SIT70188.1 | ispH | SAMN05216526_1256 | SAMN05216526_1255 | FKBP-type peptidyl-prolyl cis-trans isomerase SlpA. | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 0.853 |
SIT70188.1 | lspA | SAMN05216526_1256 | SAMN05216526_1257 | FKBP-type peptidyl-prolyl cis-trans isomerase SlpA. | Signal peptidase II Aspartic peptidase. MEROPS family A08; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. | 0.963 |
SIT70188.1 | murJ | SAMN05216526_1256 | SAMN05216526_1260 | FKBP-type peptidyl-prolyl cis-trans isomerase SlpA. | Putative peptidoglycan lipid II flippase; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.605 |
SIT70188.1 | rpsT | SAMN05216526_1256 | SAMN05216526_1261 | FKBP-type peptidyl-prolyl cis-trans isomerase SlpA. | SSU ribosomal protein S20P; Binds directly to 16S ribosomal RNA. | 0.491 |
SIT70201.1 | SIT70188.1 | SAMN05216526_1259 | SAMN05216526_1256 | Riboflavin kinase / FMN adenylyltransferase; Belongs to the ribF family. | FKBP-type peptidyl-prolyl cis-trans isomerase SlpA. | 0.789 |
SIT70201.1 | ileS | SAMN05216526_1259 | SAMN05216526_1258 | Riboflavin kinase / FMN adenylyltransferase; Belongs to the ribF family. | Isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | 0.953 |
SIT70201.1 | ispH | SAMN05216526_1259 | SAMN05216526_1255 | Riboflavin kinase / FMN adenylyltransferase; Belongs to the ribF family. | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 0.769 |
SIT70201.1 | lspA | SAMN05216526_1259 | SAMN05216526_1257 | Riboflavin kinase / FMN adenylyltransferase; Belongs to the ribF family. | Signal peptidase II Aspartic peptidase. MEROPS family A08; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. | 0.860 |
SIT70201.1 | murJ | SAMN05216526_1259 | SAMN05216526_1260 | Riboflavin kinase / FMN adenylyltransferase; Belongs to the ribF family. | Putative peptidoglycan lipid II flippase; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.931 |
SIT70201.1 | rpsT | SAMN05216526_1259 | SAMN05216526_1261 | Riboflavin kinase / FMN adenylyltransferase; Belongs to the ribF family. | SSU ribosomal protein S20P; Binds directly to 16S ribosomal RNA. | 0.602 |
ftsI | ftsW | SAMN05216526_0700 | SAMN05216526_0695 | Peptidoglycan synthetase FtsI; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | Cell division-specific peptidoglycan biosynthesis regulator FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | 0.998 |
ftsI | mraY | SAMN05216526_0700 | SAMN05216526_0697 | Peptidoglycan synthetase FtsI; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.991 |
ftsI | murA | SAMN05216526_0700 | SAMN05216526_0720 | Peptidoglycan synthetase FtsI; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.755 |
ftsI | murJ | SAMN05216526_0700 | SAMN05216526_1260 | Peptidoglycan synthetase FtsI; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | Putative peptidoglycan lipid II flippase; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.620 |
ftsW | ftsI | SAMN05216526_0695 | SAMN05216526_0700 | Cell division-specific peptidoglycan biosynthesis regulator FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | Peptidoglycan synthetase FtsI; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | 0.998 |
ftsW | mraY | SAMN05216526_0695 | SAMN05216526_0697 | Cell division-specific peptidoglycan biosynthesis regulator FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.993 |
ftsW | murA | SAMN05216526_0695 | SAMN05216526_0720 | Cell division-specific peptidoglycan biosynthesis regulator FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.770 |
ftsW | murJ | SAMN05216526_0695 | SAMN05216526_1260 | Cell division-specific peptidoglycan biosynthesis regulator FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | Putative peptidoglycan lipid II flippase; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.559 |