STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIT73072.1Citrate synthase; Belongs to the citrate synthase family. (432 aa)    
Predicted Functional Partners:
SIT70292.1
Glutamate synthase (NADH) large subunit.
    
 0.949
SIT65966.1
Dihydrolipoamide dehydrogenase.
  
 0.943
SIT65989.1
Fumarase, class I, homodimeric; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
 
 0.935
mdh
Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
  
 0.928
sucC
succinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 0.905
SIT65766.1
Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
   
 0.901
SIT66014.1
Aconitase /2-methylcitrate dehydratase (trans-methylaconitate-forming).
   
 0.899
SIT65788.1
Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+).
  
 0.897
SIT73926.1
Succinate dehydrogenase subunit B; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
  
 0.868
SIT65767.1
Aconitase; Belongs to the aconitase/IPM isomerase family.
   
 
 0.857
Your Current Organism:
Ectothiorhodosinus mongolicus
NCBI taxonomy Id: 233100
Other names: DSM 15479, E. mongolicus, Ectothiorhodosinus mongolicum, Ectothiorhodosinus mongolicus corrig. Gorlenko et al. 2007, UNIQEM U217, strain M9
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