STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIT73310.1Transcriptional regulator, BadM/Rrf2 family. (163 aa)    
Predicted Functional Partners:
SIT74020.1
Cysteine desulfurase; Partial gene; manually curated; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.
 
 
 0.977
SIT73327.1
Cysteine desulfurase.
  
 
  0.831
hscB
Co-chaperone protein HscB; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family.
  
  
 0.746
SIT73306.1
Serine O-acetyltransferase.
     
 0.706
trmJ
tRNA/rRNA methyltransferase/tRNA (cytidine32/uridine32-2'-O)-methyltransferase; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
      0.695
SIT73798.1
Iron-binding apoprotein IscA; Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system; Belongs to the HesB/IscA family.
  
  
 0.612
SIT73973.1
Cysteine desulfurase.
   
 
  0.603
nuoN
NADH dehydrogenase subunit N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family.
      
 0.522
Your Current Organism:
Ectothiorhodosinus mongolicus
NCBI taxonomy Id: 233100
Other names: DSM 15479, E. mongolicus, Ectothiorhodosinus mongolicum, Ectothiorhodosinus mongolicus corrig. Gorlenko et al. 2007, UNIQEM U217, strain M9
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