HD_0222 protein (Haemophilus ducreyi) - STRING interaction network

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Score

HD_0222

Conserved hypothetical protein. (130 aa)

Predicted Functional Partners:

HD_0464

0.874

clpX

0.532

clpP

0.529

HD_0216

0.473

lpxK

0.473

nfuA

0.400

Your Current Organism:

Haemophilus ducreyi

NCBI taxonomy Id: 233412
Other names: Haemophilus ducreyi 35000HP, Haemophilus ducreyi str. 35000HP, [. ducreyi 35000HP, [Haemophilus] ducreyi 35000HP

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HD_0216	HD_0222	HD_0216	HD_0222	Conserved hypothetical protein; Belongs to the UPF0434 family.	Conserved hypothetical protein.	0.473
HD_0216	clpP	HD_0216	HD_0221	Conserved hypothetical protein; Belongs to the UPF0434 family.	ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.	0.686
HD_0216	clpX	HD_0216	HD_0218	Conserved hypothetical protein; Belongs to the UPF0434 family.	ATP-dependent Clp protease, ATP-binding ClpX subunit; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.	0.687
HD_0216	lpxK	HD_0216	HD_0217	Conserved hypothetical protein; Belongs to the UPF0434 family.	Tetraacyldisaccharide 4' kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).	0.819
HD_0222	HD_0216	HD_0222	HD_0216	Conserved hypothetical protein.	Conserved hypothetical protein; Belongs to the UPF0434 family.	0.473
HD_0222	HD_0464	HD_0222	HD_0464	Conserved hypothetical protein.	Putative aminotransferase.	0.874
HD_0222	clpP	HD_0222	HD_0221	Conserved hypothetical protein.	ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.	0.529
HD_0222	clpX	HD_0222	HD_0218	Conserved hypothetical protein.	ATP-dependent Clp protease, ATP-binding ClpX subunit; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.	0.532
HD_0222	lpxK	HD_0222	HD_0217	Conserved hypothetical protein.	Tetraacyldisaccharide 4' kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).	0.473
HD_0222	nfuA	HD_0222	HD_0378	Conserved hypothetical protein.	Transformation locus protein OrfG-like protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.	0.400
HD_0464	HD_0222	HD_0464	HD_0222	Putative aminotransferase.	Conserved hypothetical protein.	0.874
clpP	HD_0216	HD_0221	HD_0216	ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.	Conserved hypothetical protein; Belongs to the UPF0434 family.	0.686
clpP	HD_0222	HD_0221	HD_0222	ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.	Conserved hypothetical protein.	0.529
clpP	clpX	HD_0221	HD_0218	ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.	ATP-dependent Clp protease, ATP-binding ClpX subunit; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.	0.999
clpP	lpxK	HD_0221	HD_0217	ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.	Tetraacyldisaccharide 4' kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).	0.682
clpX	HD_0216	HD_0218	HD_0216	ATP-dependent Clp protease, ATP-binding ClpX subunit; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.	Conserved hypothetical protein; Belongs to the UPF0434 family.	0.687
clpX	HD_0222	HD_0218	HD_0222	ATP-dependent Clp protease, ATP-binding ClpX subunit; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.	Conserved hypothetical protein.	0.532
clpX	clpP	HD_0218	HD_0221	ATP-dependent Clp protease, ATP-binding ClpX subunit; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.	ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.	0.999
clpX	lpxK	HD_0218	HD_0217	ATP-dependent Clp protease, ATP-binding ClpX subunit; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.	Tetraacyldisaccharide 4' kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).	0.682
lpxK	HD_0216	HD_0217	HD_0216	Tetraacyldisaccharide 4' kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).	Conserved hypothetical protein; Belongs to the UPF0434 family.	0.819