STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
degPPeriplasmic serine protease do; Belongs to the peptidase S1C family. (472 aa)    
Predicted Functional Partners:
momp
Major outer membrane protein; Belongs to the outer membrane OOP (TC 1.B.6) superfamily.
    
 
 0.799
ompA2
Major outer membrane protein-like protein, OmpA2; Belongs to the outer membrane OOP (TC 1.B.6) superfamily.
    
 
 0.799
rseA
Possible sigma-E factor negative regulatory protein; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cyto [...]
 
 
 0.742
surA
Survival protein SurA-like protein; Peptidyl-prolyl cis-trans isomerase.
     
 0.662
cpxA
Sensor kinase CpxA.
  
 0.644
dsbA
Probable thiol:disulfide interchange protein.
   
  
 0.634
znuA
Periplasmic zinc transporter; Involved in the high-affinity zinc uptake transport system; Belongs to the bacterial solute-binding protein 9 family.
      
 0.620
wecF
TDP-Fuc4NAc:lipid II Fuc4NAc transferase.
   
 0.567
kefB
Glutathione-regulated potassium-efflux system protein; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
     
 0.559
HD_0259
ABC transporter ATP binding protein.
  
    0.461
Your Current Organism:
Haemophilus ducreyi
NCBI taxonomy Id: 233412
Other names: Haemophilus ducreyi 35000HP, Haemophilus ducreyi str. 35000HP, [. ducreyi 35000HP, [Haemophilus] ducreyi 35000HP
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.