node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
HD_0254 | grxD | HD_0254 | HD_0324 | Conserved hypothetical protein; Belongs to the BolA/IbaG family. | Conserved glutaredoxin-like protein; Monothiol glutaredoxin involved in the biogenesis of iron- sulfur clusters. | 0.607 |
HD_0700 | gloA | HD_0700 | HD_0610 | Putative peroxiredoxin/glutaredoxin family protein. | Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. | 0.566 |
HD_0700 | grxD | HD_0700 | HD_0324 | Putative peroxiredoxin/glutaredoxin family protein. | Conserved glutaredoxin-like protein; Monothiol glutaredoxin involved in the biogenesis of iron- sulfur clusters. | 0.685 |
HD_0700 | nfuA | HD_0700 | HD_0378 | Putative peroxiredoxin/glutaredoxin family protein. | Transformation locus protein OrfG-like protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.691 |
bolA | grxD | HD_1791 | HD_0324 | Putative transcriptional regulator, BolA; Belongs to the BolA/IbaG family. | Conserved glutaredoxin-like protein; Monothiol glutaredoxin involved in the biogenesis of iron- sulfur clusters. | 0.984 |
bolA | nfuA | HD_1791 | HD_0378 | Putative transcriptional regulator, BolA; Belongs to the BolA/IbaG family. | Transformation locus protein OrfG-like protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.640 |
gloA | HD_0700 | HD_0610 | HD_0700 | Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. | Putative peroxiredoxin/glutaredoxin family protein. | 0.566 |
gloA | grxD | HD_0610 | HD_0324 | Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. | Conserved glutaredoxin-like protein; Monothiol glutaredoxin involved in the biogenesis of iron- sulfur clusters. | 0.509 |
grxD | HD_0254 | HD_0324 | HD_0254 | Conserved glutaredoxin-like protein; Monothiol glutaredoxin involved in the biogenesis of iron- sulfur clusters. | Conserved hypothetical protein; Belongs to the BolA/IbaG family. | 0.607 |
grxD | HD_0700 | HD_0324 | HD_0700 | Conserved glutaredoxin-like protein; Monothiol glutaredoxin involved in the biogenesis of iron- sulfur clusters. | Putative peroxiredoxin/glutaredoxin family protein. | 0.685 |
grxD | bolA | HD_0324 | HD_1791 | Conserved glutaredoxin-like protein; Monothiol glutaredoxin involved in the biogenesis of iron- sulfur clusters. | Putative transcriptional regulator, BolA; Belongs to the BolA/IbaG family. | 0.984 |
grxD | gloA | HD_0324 | HD_0610 | Conserved glutaredoxin-like protein; Monothiol glutaredoxin involved in the biogenesis of iron- sulfur clusters. | Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. | 0.509 |
grxD | kdkA | HD_0324 | HD_1101 | Conserved glutaredoxin-like protein; Monothiol glutaredoxin involved in the biogenesis of iron- sulfur clusters. | 3-deoxy-D-mannooctulosonic acid kinase; Catalyzes the ATP-dependent phosphorylation of the 3-deoxy-D- manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position; Belongs to the protein kinase superfamily. KdkA/RfaP family. | 0.508 |
grxD | map | HD_0324 | HD_0248 | Conserved glutaredoxin-like protein; Monothiol glutaredoxin involved in the biogenesis of iron- sulfur clusters. | Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. | 0.505 |
grxD | nfuA | HD_0324 | HD_0378 | Conserved glutaredoxin-like protein; Monothiol glutaredoxin involved in the biogenesis of iron- sulfur clusters. | Transformation locus protein OrfG-like protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.778 |
grxD | recR | HD_0324 | HD_0325 | Conserved glutaredoxin-like protein; Monothiol glutaredoxin involved in the biogenesis of iron- sulfur clusters. | Recombination DNA repair protein; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. | 0.595 |
grxD | thrS | HD_0324 | HD_1803 | Conserved glutaredoxin-like protein; Monothiol glutaredoxin involved in the biogenesis of iron- sulfur clusters. | threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr). | 0.531 |
grxD | visC | HD_0324 | HD_0582 | Conserved glutaredoxin-like protein; Monothiol glutaredoxin involved in the biogenesis of iron- sulfur clusters. | Probable monoxygenase. | 0.559 |
kdkA | grxD | HD_1101 | HD_0324 | 3-deoxy-D-mannooctulosonic acid kinase; Catalyzes the ATP-dependent phosphorylation of the 3-deoxy-D- manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position; Belongs to the protein kinase superfamily. KdkA/RfaP family. | Conserved glutaredoxin-like protein; Monothiol glutaredoxin involved in the biogenesis of iron- sulfur clusters. | 0.508 |
map | grxD | HD_0248 | HD_0324 | Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. | Conserved glutaredoxin-like protein; Monothiol glutaredoxin involved in the biogenesis of iron- sulfur clusters. | 0.505 |