STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
exbDBiopolymer transport protein; Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates. (129 aa)    
Predicted Functional Partners:
exbB
Biopolymer transport protein; Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates. Protects ExbD from proteolytic degradation and functionally stabilizes TonB (By similarity).
 
 
 0.998
tonB
TobB energy transducing protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Required for heme utilization and virulence (By similarity); Belongs to the TonB family.
 
 
 0.991
tolQ
Colicin transport protein, TolQ; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
 
 
 0.945
tolR
TolR protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
  
   
 0.872
HD_1439
Hypothetical protein.
  
 
 0.729
ribAB
Riboflavin biosynthesis protein ribA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
   
 
 0.666
HD_1939
Conserved hypothetical protein.
   
  
 0.500
HD_0326
Conserved hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
       0.476
pal
18K peptidoglycan-associated outer membrane lipoprotein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
 
 
 0.465
momp
Major outer membrane protein; Belongs to the outer membrane OOP (TC 1.B.6) superfamily.
   
 
 0.427
Your Current Organism:
Haemophilus ducreyi
NCBI taxonomy Id: 233412
Other names: Haemophilus ducreyi 35000HP, Haemophilus ducreyi str. 35000HP, [. ducreyi 35000HP, [Haemophilus] ducreyi 35000HP
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.