node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
HD_0222 | HD_0464 | HD_0222 | HD_0464 | Conserved hypothetical protein. | Putative aminotransferase. | 0.817 |
HD_0461 | HD_0463 | HD_0461 | HD_0463 | Putative amino-acid transporter, sodium-dependent. | Hypothetical protein. | 0.554 |
HD_0461 | HD_0464 | HD_0461 | HD_0464 | Putative amino-acid transporter, sodium-dependent. | Putative aminotransferase. | 0.554 |
HD_0463 | HD_0461 | HD_0463 | HD_0461 | Hypothetical protein. | Putative amino-acid transporter, sodium-dependent. | 0.554 |
HD_0463 | HD_0464 | HD_0463 | HD_0464 | Hypothetical protein. | Putative aminotransferase. | 0.773 |
HD_0463 | pfkA | HD_0463 | HD_0465 | Hypothetical protein. | Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. | 0.515 |
HD_0464 | HD_0222 | HD_0464 | HD_0222 | Putative aminotransferase. | Conserved hypothetical protein. | 0.817 |
HD_0464 | HD_0461 | HD_0464 | HD_0461 | Putative aminotransferase. | Putative amino-acid transporter, sodium-dependent. | 0.554 |
HD_0464 | HD_0463 | HD_0464 | HD_0463 | Putative aminotransferase. | Hypothetical protein. | 0.773 |
HD_0464 | cdtB | HD_0464 | HD_0903 | Putative aminotransferase. | Cytolethal distending toxin protein B. | 0.830 |
HD_0464 | fdhD | HD_0464 | HD_1113 | Putative aminotransferase. | Formate dehydrogenase formation protein; Required for formate dehydrogenase (FDH) activity. Belongs to the FdhD family. | 0.528 |
HD_0464 | iscS | HD_0464 | HD_1082 | Putative aminotransferase. | Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. | 0.614 |
HD_0464 | iscU | HD_0464 | HD_1083 | Putative aminotransferase. | NifU-like protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | 0.994 |
HD_0464 | macB | HD_0464 | HD_1019 | Putative aminotransferase. | Macrolide-specific ABC-type efflux carrier; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.464 |
HD_0464 | pfkA | HD_0464 | HD_0465 | Putative aminotransferase. | Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. | 0.516 |
HD_0464 | polA | HD_0464 | HD_1236 | Putative aminotransferase. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.461 |
cdtB | HD_0464 | HD_0903 | HD_0464 | Cytolethal distending toxin protein B. | Putative aminotransferase. | 0.830 |
fdhD | HD_0464 | HD_1113 | HD_0464 | Formate dehydrogenase formation protein; Required for formate dehydrogenase (FDH) activity. Belongs to the FdhD family. | Putative aminotransferase. | 0.528 |
fdhD | iscS | HD_1113 | HD_1082 | Formate dehydrogenase formation protein; Required for formate dehydrogenase (FDH) activity. Belongs to the FdhD family. | Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. | 0.711 |
iscS | HD_0464 | HD_1082 | HD_0464 | Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. | Putative aminotransferase. | 0.614 |