| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| HD_1023 | glnA | HD_1023 | HD_0750 | Histidine triad, HIT-like protein. | Glutamine synthetase; Glutamate--ammonia ligase. | 0.729 |
| alr | glnA | HD_0624 | HD_0750 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | Glutamine synthetase; Glutamate--ammonia ligase. | 0.818 |
| alr | murI | HD_0624 | HD_1906 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.673 |
| carA | carB | HD_0235 | HD_0233 | Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | Carbamoyl-phosphate synthase, large subunit. | 0.999 |
| carA | glmS | HD_0235 | HD_1894 | Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.908 |
| carA | glnA | HD_0235 | HD_0750 | Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | Glutamine synthetase; Glutamate--ammonia ligase. | 0.915 |
| carB | carA | HD_0233 | HD_0235 | Carbamoyl-phosphate synthase, large subunit. | Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | 0.999 |
| carB | glmS | HD_0233 | HD_1894 | Carbamoyl-phosphate synthase, large subunit. | Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.932 |
| carB | glnA | HD_0233 | HD_0750 | Carbamoyl-phosphate synthase, large subunit. | Glutamine synthetase; Glutamate--ammonia ligase. | 0.932 |
| carB | gltX | HD_0233 | HD_0320 | Carbamoyl-phosphate synthase, large subunit. | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | 0.434 |
| glmS | carA | HD_1894 | HD_0235 | Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | 0.908 |
| glmS | carB | HD_1894 | HD_0233 | Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Carbamoyl-phosphate synthase, large subunit. | 0.932 |
| glmS | glnA | HD_1894 | HD_0750 | Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Glutamine synthetase; Glutamate--ammonia ligase. | 0.927 |
| glnA | HD_1023 | HD_0750 | HD_1023 | Glutamine synthetase; Glutamate--ammonia ligase. | Histidine triad, HIT-like protein. | 0.729 |
| glnA | alr | HD_0750 | HD_0624 | Glutamine synthetase; Glutamate--ammonia ligase. | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.818 |
| glnA | carA | HD_0750 | HD_0235 | Glutamine synthetase; Glutamate--ammonia ligase. | Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | 0.915 |
| glnA | carB | HD_0750 | HD_0233 | Glutamine synthetase; Glutamate--ammonia ligase. | Carbamoyl-phosphate synthase, large subunit. | 0.932 |
| glnA | glmS | HD_0750 | HD_1894 | Glutamine synthetase; Glutamate--ammonia ligase. | Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.927 |
| glnA | glnE | HD_0750 | HD_1709 | Glutamine synthetase; Glutamate--ammonia ligase. | Glutamate ammonia ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...] | 0.816 |
| glnA | gltX | HD_0750 | HD_0320 | Glutamine synthetase; Glutamate--ammonia ligase. | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. | 0.817 |