| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| HD_0800 | HD_0801 | HD_0800 | HD_0801 | Conserved hypothetical protein. | Conserved possible phosphoheptose isomerase. | 0.786 |
| HD_0800 | HD_0802 | HD_0800 | HD_0802 | Conserved hypothetical protein. | Conserved hypothetical protein; Belongs to the UPF0102 family. | 0.737 |
| HD_0800 | lppC | HD_0800 | HD_0803 | Conserved hypothetical protein. | Lipoprotein C-like protein; Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a). | 0.743 |
| HD_0800 | rsmI | HD_0800 | HD_0804 | Conserved hypothetical protein. | Conserved hypothetical protein; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. | 0.547 |
| HD_0801 | HD_0800 | HD_0801 | HD_0800 | Conserved possible phosphoheptose isomerase. | Conserved hypothetical protein. | 0.786 |
| HD_0801 | HD_0802 | HD_0801 | HD_0802 | Conserved possible phosphoheptose isomerase. | Conserved hypothetical protein; Belongs to the UPF0102 family. | 0.800 |
| HD_0801 | dnaA | HD_0801 | HD_0851 | Conserved possible phosphoheptose isomerase. | Chromosomal replication initiator protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | 0.522 |
| HD_0801 | gmhB | HD_0801 | HD_1666 | Conserved possible phosphoheptose isomerase. | Probable phosphatase; Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate by removing the phosphate group at the C-7 position; Belongs to the GmhB family. | 0.896 |
| HD_0801 | kpsF | HD_0801 | HD_1168 | Conserved possible phosphoheptose isomerase. | Arabinose-5-phosphate isomerase. | 0.450 |
| HD_0801 | lpcA | HD_0801 | HD_1228 | Conserved possible phosphoheptose isomerase. | Phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate; Belongs to the SIS family. GmhA subfamily. | 0.924 |
| HD_0801 | lppC | HD_0801 | HD_0803 | Conserved possible phosphoheptose isomerase. | Lipoprotein C-like protein; Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a). | 0.799 |
| HD_0801 | rsmI | HD_0801 | HD_0804 | Conserved possible phosphoheptose isomerase. | Conserved hypothetical protein; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. | 0.571 |
| HD_0801 | waaE | HD_0801 | HD_1182 | Conserved possible phosphoheptose isomerase. | ADP-heptose synthase; Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7- phosphate at the C-1 position to selectively form D-glycero-beta-D- manno-heptose-1,7-bisphosphate; In the N-terminal section; belongs to the carbohydrate kinase PfkB family. | 0.965 |
| HD_0801 | waaF | HD_0801 | HD_0653 | Conserved possible phosphoheptose isomerase. | ADP-heptose--lipooligosaccharide heptosyltransferase II. | 0.507 |
| HD_0802 | HD_0800 | HD_0802 | HD_0800 | Conserved hypothetical protein; Belongs to the UPF0102 family. | Conserved hypothetical protein. | 0.737 |
| HD_0802 | HD_0801 | HD_0802 | HD_0801 | Conserved hypothetical protein; Belongs to the UPF0102 family. | Conserved possible phosphoheptose isomerase. | 0.800 |
| HD_0802 | lppC | HD_0802 | HD_0803 | Conserved hypothetical protein; Belongs to the UPF0102 family. | Lipoprotein C-like protein; Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a). | 0.789 |
| HD_0802 | rsmI | HD_0802 | HD_0804 | Conserved hypothetical protein; Belongs to the UPF0102 family. | Conserved hypothetical protein; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. | 0.579 |
| dnaA | HD_0801 | HD_0851 | HD_0801 | Chromosomal replication initiator protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | Conserved possible phosphoheptose isomerase. | 0.522 |
| dnaA | lpcA | HD_0851 | HD_1228 | Chromosomal replication initiator protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | Phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate; Belongs to the SIS family. GmhA subfamily. | 0.522 |