Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
HD_0856Conserved hypothetical protein. (288 aa)    
Predicted Functional Partners:
hemK
Protein-glutamine N-methyl transferase; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
       0.845
kdsA
2-dehydro-3-deoxyphosphooctonate aldolase; 3-deoxy-D-manno-octulosonic acid 8-phosphate synthetase; Belongs to the KdsA family.
  
    0.782
lolC
Lipoprotein releasing system transmembrane protein.
       0.715
prfA
Peptide chain release factor 1 (RF-1); Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
       0.648
lolE
Lipoprotein releasing system transmembrane protein.
       0.508
lolD
Lipoprotein releasing system ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
       0.498
HD_1708
Conserved hypothetical protein; Belongs to the UPF0231 family.
  
     0.482
fimC
Probable fimbrial outer membrane usher protein.
  
     0.436
HD_1835
Putative polysaccharide biosynthesis protein.
  
     0.425
HD_0637
Conserved hypothetical protein.
  
     0.416
Your Current Organism:
Haemophilus ducreyi
NCBI taxonomy Id: 233412
Other names: Haemophilus ducreyi 35000HP, Haemophilus ducreyi str. 35000HP, [. ducreyi 35000HP, [Haemophilus] ducreyi 35000HP
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