STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HD_0907Hypothetical protein. (193 aa)    
Predicted Functional Partners:
iscS
Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
  
 0.776
iscU
NifU-like protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
  
 0.759
lsgD
Possible lipooligosaccharide N-acetylglucosamine glycosyltransferase.
  
     0.739
aphA
AphA (smp-like) protein.
  
     0.711
lgtB
Lipooligosaccharide galactosyltransferase II.
  
     0.704
lbgB
Lipooligosaccharide D-glycero-D-manno-heptosyltransferase.
  
   0.699
nfuA
Transformation locus protein OrfG-like protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.
  
 
 0.678
HD_1320
Putative integral membrane protein.
  
     0.667
fabG
3-oxoacyl-(acyl-carrier-protein) reductase, truncated.
   
 
 0.641
LapB
Putative membrane protein.
  
     0.639
Your Current Organism:
Haemophilus ducreyi
NCBI taxonomy Id: 233412
Other names: Haemophilus ducreyi 35000HP, Haemophilus ducreyi str. 35000HP, [. ducreyi 35000HP, [Haemophilus] ducreyi 35000HP
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.