| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| HD_0985 | HD_0986 | HD_0985 | HD_0986 | Converved hypothetical protein; Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle; Belongs to the methyltransferase superfamily. RsmD family. | Conserved hypothetical protein; Belongs to the UPF0263 family. | 0.623 |
| HD_0985 | ftsY | HD_0985 | HD_0984 | Converved hypothetical protein; Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle; Belongs to the methyltransferase superfamily. RsmD family. | Cell division protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. | 0.837 |
| HD_0985 | hpaC | HD_0985 | HD_0987 | Converved hypothetical protein; Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle; Belongs to the methyltransferase superfamily. RsmD family. | 4-hydroxyphenylacetic acid hydroxylase putative coupling protein; Flavin:NADH oxidoreductase component. | 0.591 |
| HD_0986 | HD_0985 | HD_0986 | HD_0985 | Conserved hypothetical protein; Belongs to the UPF0263 family. | Converved hypothetical protein; Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle; Belongs to the methyltransferase superfamily. RsmD family. | 0.623 |
| HD_0986 | ftsY | HD_0986 | HD_0984 | Conserved hypothetical protein; Belongs to the UPF0263 family. | Cell division protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. | 0.453 |
| HD_0986 | hpaC | HD_0986 | HD_0987 | Conserved hypothetical protein; Belongs to the UPF0263 family. | 4-hydroxyphenylacetic acid hydroxylase putative coupling protein; Flavin:NADH oxidoreductase component. | 0.733 |
| ftsY | HD_0985 | HD_0984 | HD_0985 | Cell division protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. | Converved hypothetical protein; Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle; Belongs to the methyltransferase superfamily. RsmD family. | 0.837 |
| ftsY | HD_0986 | HD_0984 | HD_0986 | Cell division protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. | Conserved hypothetical protein; Belongs to the UPF0263 family. | 0.453 |
| ftsY | hpaC | HD_0984 | HD_0987 | Cell division protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. | 4-hydroxyphenylacetic acid hydroxylase putative coupling protein; Flavin:NADH oxidoreductase component. | 0.437 |
| hpaC | HD_0985 | HD_0987 | HD_0985 | 4-hydroxyphenylacetic acid hydroxylase putative coupling protein; Flavin:NADH oxidoreductase component. | Converved hypothetical protein; Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle; Belongs to the methyltransferase superfamily. RsmD family. | 0.591 |
| hpaC | HD_0986 | HD_0987 | HD_0986 | 4-hydroxyphenylacetic acid hydroxylase putative coupling protein; Flavin:NADH oxidoreductase component. | Conserved hypothetical protein; Belongs to the UPF0263 family. | 0.733 |
| hpaC | ftsY | HD_0987 | HD_0984 | 4-hydroxyphenylacetic acid hydroxylase putative coupling protein; Flavin:NADH oxidoreductase component. | Cell division protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. | 0.437 |
| hpaC | ribAB | HD_0987 | HD_1163 | 4-hydroxyphenylacetic acid hydroxylase putative coupling protein; Flavin:NADH oxidoreductase component. | Riboflavin biosynthesis protein ribA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.598 |
| hpaC | ribE | HD_0987 | HD_1162 | 4-hydroxyphenylacetic acid hydroxylase putative coupling protein; Flavin:NADH oxidoreductase component. | Riboflavin synthase, alpha chain. | 0.900 |
| hpaC | ribF | HD_0987 | HD_0273 | 4-hydroxyphenylacetic acid hydroxylase putative coupling protein; Flavin:NADH oxidoreductase component. | Riboflavin biosynthesis protein RibF; Includes riboflavin kinase, FMN adenylyltransferase; Belongs to the ribF family. | 0.905 |
| hpaC | ubiX | HD_0987 | HD_1360 | 4-hydroxyphenylacetic acid hydroxylase putative coupling protein; Flavin:NADH oxidoreductase component. | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. | 0.900 |
| ribAB | hpaC | HD_1163 | HD_0987 | Riboflavin biosynthesis protein ribA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 4-hydroxyphenylacetic acid hydroxylase putative coupling protein; Flavin:NADH oxidoreductase component. | 0.598 |
| ribAB | ribE | HD_1163 | HD_1162 | Riboflavin biosynthesis protein ribA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | Riboflavin synthase, alpha chain. | 0.999 |
| ribAB | ribF | HD_1163 | HD_0273 | Riboflavin biosynthesis protein ribA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | Riboflavin biosynthesis protein RibF; Includes riboflavin kinase, FMN adenylyltransferase; Belongs to the ribF family. | 0.639 |
| ribE | hpaC | HD_1162 | HD_0987 | Riboflavin synthase, alpha chain. | 4-hydroxyphenylacetic acid hydroxylase putative coupling protein; Flavin:NADH oxidoreductase component. | 0.900 |