STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
purAAdenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (432 aa)    
Predicted Functional Partners:
purB
Adenylosuccinate lyase; Adenylosuccinase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
 
 0.991
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
 
 
 0.986
purH
Bifunctional purine biosynthesis protein, N-terminal truncated.
  
 0.973
hpt
Hypoxanthine phosphoribosyl transferase (HPRT); Belongs to the purine/pyrimidine phosphoribosyltransferase family.
  
 
 0.942
argG
Argininosuccinate synthetase; Citrulline--aspartate ligase; Belongs to the argininosuccinate synthase family. Type 2 subfamily.
   
 
 0.940
aspC
Aspartate aminotransferase; Transaminase A; ASPAT.
  
 0.916
surE
Acid phosphatase stationary-phase survival protein; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
    
 0.907
HD_1029
Putative haloacid dehalogenase-like hydrolase.
    
  0.905
aspA
Aspartate ammonia-lyase.
     
 0.901
ansB
L-asparaginase II; Belongs to the asparaginase 1 family.
     
  0.900
Your Current Organism:
Haemophilus ducreyi
NCBI taxonomy Id: 233412
Other names: Haemophilus ducreyi 35000HP, Haemophilus ducreyi str. 35000HP, [. ducreyi 35000HP, [Haemophilus] ducreyi 35000HP
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.