| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| dacA | ftsI | HD_2016 | HD_0241 | Penicillin-binding protein 5; D-alanyl-D-alanine carboxypeptidase fraction A; Belongs to the peptidase S11 family. | Penicillin-binding protein 3; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | 0.939 |
| dacA | mrcA | HD_2016 | HD_0426 | Penicillin-binding protein 5; D-alanyl-D-alanine carboxypeptidase fraction A; Belongs to the peptidase S11 family. | Penicillin-binding protein 1A. | 0.928 |
| dacA | mrdA | HD_2016 | HD_2020 | Penicillin-binding protein 5; D-alanyl-D-alanine carboxypeptidase fraction A; Belongs to the peptidase S11 family. | Penicillin binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | 0.966 |
| dacA | mrdB | HD_2016 | HD_2019 | Penicillin-binding protein 5; D-alanyl-D-alanine carboxypeptidase fraction A; Belongs to the peptidase S11 family. | Rod-shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. | 0.658 |
| dacA | mreB | HD_2016 | HD_1292 | Penicillin-binding protein 5; D-alanyl-D-alanine carboxypeptidase fraction A; Belongs to the peptidase S11 family. | Rod shape-determining protein MreB. | 0.522 |
| dacA | rlmH | HD_2016 | HD_2022 | Penicillin-binding protein 5; D-alanyl-D-alanine carboxypeptidase fraction A; Belongs to the peptidase S11 family. | Conserved hypotheical protein; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.601 |
| ftsI | dacA | HD_0241 | HD_2016 | Penicillin-binding protein 3; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | Penicillin-binding protein 5; D-alanyl-D-alanine carboxypeptidase fraction A; Belongs to the peptidase S11 family. | 0.939 |
| ftsI | ftsL | HD_0241 | HD_0240 | Penicillin-binding protein 3; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | Cell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | 0.994 |
| ftsI | ftsQ | HD_0241 | HD_0820 | Penicillin-binding protein 3; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | Cell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | 0.974 |
| ftsI | ftsW | HD_0241 | HD_0246 | Penicillin-binding protein 3; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | Cell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | 0.995 |
| ftsI | mrcA | HD_0241 | HD_0426 | Penicillin-binding protein 3; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | Penicillin-binding protein 1A. | 0.965 |
| ftsI | mrdA | HD_0241 | HD_2020 | Penicillin-binding protein 3; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | Penicillin binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | 0.950 |
| ftsI | mrdB | HD_0241 | HD_2019 | Penicillin-binding protein 3; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | Rod-shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. | 0.907 |
| ftsI | mreB | HD_0241 | HD_1292 | Penicillin-binding protein 3; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | Rod shape-determining protein MreB. | 0.736 |
| ftsI | mreC | HD_0241 | HD_1293 | Penicillin-binding protein 3; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | Rod shape-determining protein MreC. | 0.676 |
| ftsL | ftsI | HD_0240 | HD_0241 | Cell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | Penicillin-binding protein 3; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | 0.994 |
| ftsL | ftsQ | HD_0240 | HD_0820 | Cell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | Cell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | 0.987 |
| ftsL | ftsW | HD_0240 | HD_0246 | Cell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | Cell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | 0.979 |
| ftsL | mrdA | HD_0240 | HD_2020 | Cell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | Penicillin binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | 0.779 |
| ftsL | mrdB | HD_0240 | HD_2019 | Cell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | Rod-shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. | 0.799 |