STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
hypAZn finger protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. (126 aa)    
Predicted Functional Partners:
JV46_24300
Hydrogenase accessory protein HypB.
 
 
 0.982
hypF
(Ni-Fe)-hydrogenase maturation protein HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.
 
   
 0.979
hupL
(Ni-Fe)-uptake hydrogenase HupSL, subunit L; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
 
 
 0.965
hypC
Hydrogenase assembly chaperone HypC.
 
  
 0.952
JV46_24290
Hydrogenase maturation factor; Belongs to the HypD family.
 
  
 0.938
hypE
Hydrogenase expression/formation protein HypE.
 
  
 0.927
hupS
(Ni-Fe)-uptake hydrogenase HupSL, subunit S.
 
  
 0.892
ureG
Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
 
 
 0.884
JV46_26660
Hydrogenase maturation protease.
 
  
 0.869
JV46_03340
Hypothetical protein; Potentially involved in exopolysaccharide biosynthesis.
   
   0.663
Your Current Organism:
Solemya velum
NCBI taxonomy Id: 2340
Other names: S. velum gill symbiont, Solemya velum gill symbiont, Solemya velum symbiont
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