| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| carB | glmS | SOPEG_1375 | SOPEG_0017 | COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); Belongs to the CarB family. | Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.935 |
| carB | glnA | SOPEG_1375 | SOPEG_3351 | COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); Belongs to the CarB family. | COG0174 Glutamine synthetase. | 0.936 |
| carB | gltD | SOPEG_1375 | SOPEG_0178 | COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); Belongs to the CarB family. | COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases. | 0.914 |
| carB | purF | SOPEG_1375 | SOPEG_2869 | COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); Belongs to the CarB family. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.988 |
| glmM | glmS | SOPEG_1259 | SOPEG_0017 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.969 |
| glmM | glmU | SOPEG_1259 | SOPEG_0016 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.994 |
| glmM | nagA | SOPEG_1259 | SOPEG_0670 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | COG1820 N-acetylglucosamine-6-phosphate deacetylase. | 0.914 |
| glmM | nagB | SOPEG_1259 | SOPEG_0671 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | Glucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. | 0.925 |
| glmM | pgi | SOPEG_1259 | SOPEG_3663 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | COG0166 Glucose-6-phosphate isomerase; Belongs to the GPI family. | 0.438 |
| glmS | carB | SOPEG_0017 | SOPEG_1375 | Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); Belongs to the CarB family. | 0.935 |
| glmS | glmM | SOPEG_0017 | SOPEG_1259 | Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.969 |
| glmS | glmU | SOPEG_0017 | SOPEG_0016 | Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.993 |
| glmS | glnA | SOPEG_0017 | SOPEG_3351 | Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | COG0174 Glutamine synthetase. | 0.931 |
| glmS | gltD | SOPEG_0017 | SOPEG_0178 | Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases. | 0.919 |
| glmS | manA | SOPEG_0017 | SOPEG_2342 | Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | COG1482 Phosphomannose isomerase; Belongs to the mannose-6-phosphate isomerase type 1 family. | 0.919 |
| glmS | nagA | SOPEG_0017 | SOPEG_0670 | Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | COG1820 N-acetylglucosamine-6-phosphate deacetylase. | 0.927 |
| glmS | nagB | SOPEG_0017 | SOPEG_0671 | Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Glucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. | 0.937 |
| glmS | pgi | SOPEG_0017 | SOPEG_3663 | Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | COG0166 Glucose-6-phosphate isomerase; Belongs to the GPI family. | 0.933 |
| glmS | purF | SOPEG_0017 | SOPEG_2869 | Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.919 |
| glmU | glmM | SOPEG_0016 | SOPEG_1259 | Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.994 |
