STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lptALptA protein essential for LPS transport across the periplasm; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm. (183 aa)    
Predicted Functional Partners:
lptC
Uncharacterized protein YrbK; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family.
 
 0.999
lptB
Lipopolysaccharide ABC transporter ATP-binding protein LptB; COG1137 ABC-type (unclassified) transport system, ATPase component.
  
 
 0.996
lptD
LPS-assembly protein LptD; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
 
 
 0.861
kdsC
3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC; Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family.
  
    0.812
ypjD
Putative membrane protein; COG4536 Putative Mg2+ and Co2+ transporter CorB; hypothetical protein.
  
     0.624
flgC2
COG1558 Flagellar basal body rod protein; Belongs to the flagella basal body rod proteins family.
    
   0.608
yceD
Protein clustered with ribosomal protein L32p; COG0424 Nucleotide-binding protein implicated in inhibition of septum formation; hypothetical protein.
  
     0.595
bamA
Outer membrane protein assembly factor YaeT; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamD, the core component of the assembly machinery.
  
  
 0.541
hflD
Lysogenization regulator; COG2915 Uncharacterized protein involved in purine metabolism.
  
     0.533
holA
COG1466 DNA polymerase III, delta subunit.
 
     0.532
Your Current Organism:
Sodalis pierantonius
NCBI taxonomy Id: 2342
Other names: C. Sodalis pierantonius str. SOPE, Candidatus Sodalis pierantonius str. SOPE, SOPE, Sitophilus oryzae endosymbiont, Sitophilus oryzae primary endosymbiont, Sitophilus oryzae principal endosymbiont, primary endosymbiont of Sitophilus oryzae
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