STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mazGNucleoside triphosphate pyrophosphohydrolase MazG; COG1694 Predicted pyrophosphatase. (268 aa)    
Predicted Functional Partners:
relA
GTP pyrophosphokinase (P)ppGpp synthetase I; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
 
 0.981
pyrG
CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
    
  0.944
cpdA
3'5'-cyclic-nucleotide phosphodiesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.
  
  
  0.921
dcd
dCTP deaminase; Catalyzes the deamination of dCTP to dUTP.
     
 0.917
cmk
COG0283 Cytidylate kinase.
 
  
  0.913
hpt
Hypoxanthine phosphoribosyltransferase; Potential frameshift: common BLAST hit: gi|90423981|ref|YP_532351.1| glucose-methanol-choline oxidoreductase; glucose-methanol-choline oxidoreductase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
    
  0.908
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
    
  0.908
coaE
dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
    
  0.907
nudC
NADH pyrophosphatase; Potential frameshift: common BLAST hit: gi|85058116|ref|YP_453818.1| uroporphyrinogen decarboxylase; uroporphyrinogen decarboxylase; Belongs to the Nudix hydrolase family. NudC subfamily.
     
 0.904
nadR
HTH-type transcriptional regulator, transcriptional repressor of NAD biosynthesis genes; COG0488 ATPase components of ABC transporters with duplicated ATPase domains; ABC transporter ATP-binding protein.
     
 0.903
Your Current Organism:
Sodalis pierantonius
NCBI taxonomy Id: 2342
Other names: C. Sodalis pierantonius str. SOPE, Candidatus Sodalis pierantonius str. SOPE, SOPE, Sitophilus oryzae endosymbiont, Sitophilus oryzae primary endosymbiont, Sitophilus oryzae principal endosymbiont, primary endosymbiont of Sitophilus oryzae
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