node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
amiB | amiC | SOPEG_1206 | SOPEG_3430 | COG0860 N-acetylmuramoyl-L-alanine amidase. | COG0860 N-acetylmuramoyl-L-alanine amidase. | 0.941 |
amiB | envC | SOPEG_1206 | SOPEG_0893 | COG0860 N-acetylmuramoyl-L-alanine amidase. | Cell wall endopeptidase family M23/M37; COG2861 Uncharacterized protein conserved in bacteria; hypothetical protein. | 0.733 |
amiB | glpG | SOPEG_1206 | SOPEG_0301 | COG0860 N-acetylmuramoyl-L-alanine amidase. | Intramembrane serine protease GlpG; Rhomboid-type serine protease that catalyzes intramembrane proteolysis. | 0.665 |
amiB | miaA | SOPEG_1206 | SOPEG_1208 | COG0860 N-acetylmuramoyl-L-alanine amidase. | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.849 |
amiB | mrcB | SOPEG_1206 | SOPEG_0957 | COG0860 N-acetylmuramoyl-L-alanine amidase. | Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | 0.746 |
amiB | mutL | SOPEG_1206 | SOPEG_1207 | COG0860 N-acetylmuramoyl-L-alanine amidase. | DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.849 |
amiB | nlpD | SOPEG_1206 | SOPEG_1030 | COG0860 N-acetylmuramoyl-L-alanine amidase. | Lipoprotein NlpD; COG0739 Membrane proteins related to metalloendopeptidases. | 0.739 |
amiB | pal | SOPEG_1206 | SOPEG_0705 | COG0860 N-acetylmuramoyl-L-alanine amidase. | Peptidoglycan-associated outer membrane lipoprotein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. | 0.764 |
amiB | yjeE | SOPEG_1206 | SOPEG_1205 | COG0860 N-acetylmuramoyl-L-alanine amidase. | ATPase YjeE predicted to have essential role in cell wall biosynthesis; COG0802 Predicted ATPase or kinase. | 0.862 |
amiB | yjeF | SOPEG_1206 | SOPEG_1204 | COG0860 N-acetylmuramoyl-L-alanine amidase. | ADP-dependent (S)-NAD(P)H-hydrate dehydratase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to all [...] | 0.909 |
amiC | amiB | SOPEG_3430 | SOPEG_1206 | COG0860 N-acetylmuramoyl-L-alanine amidase. | COG0860 N-acetylmuramoyl-L-alanine amidase. | 0.941 |
amiC | envC | SOPEG_3430 | SOPEG_0893 | COG0860 N-acetylmuramoyl-L-alanine amidase. | Cell wall endopeptidase family M23/M37; COG2861 Uncharacterized protein conserved in bacteria; hypothetical protein. | 0.473 |
amiC | glpG | SOPEG_3430 | SOPEG_0301 | COG0860 N-acetylmuramoyl-L-alanine amidase. | Intramembrane serine protease GlpG; Rhomboid-type serine protease that catalyzes intramembrane proteolysis. | 0.614 |
amiC | mrcB | SOPEG_3430 | SOPEG_0957 | COG0860 N-acetylmuramoyl-L-alanine amidase. | Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | 0.432 |
amiC | nlpD | SOPEG_3430 | SOPEG_1030 | COG0860 N-acetylmuramoyl-L-alanine amidase. | Lipoprotein NlpD; COG0739 Membrane proteins related to metalloendopeptidases. | 0.499 |
amiC | pal | SOPEG_3430 | SOPEG_0705 | COG0860 N-acetylmuramoyl-L-alanine amidase. | Peptidoglycan-associated outer membrane lipoprotein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. | 0.447 |
amiC | yjeF | SOPEG_3430 | SOPEG_1204 | COG0860 N-acetylmuramoyl-L-alanine amidase. | ADP-dependent (S)-NAD(P)H-hydrate dehydratase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to all [...] | 0.478 |
envC | amiB | SOPEG_0893 | SOPEG_1206 | Cell wall endopeptidase family M23/M37; COG2861 Uncharacterized protein conserved in bacteria; hypothetical protein. | COG0860 N-acetylmuramoyl-L-alanine amidase. | 0.733 |
envC | amiC | SOPEG_0893 | SOPEG_3430 | Cell wall endopeptidase family M23/M37; COG2861 Uncharacterized protein conserved in bacteria; hypothetical protein. | COG0860 N-acetylmuramoyl-L-alanine amidase. | 0.473 |
envC | mrcB | SOPEG_0893 | SOPEG_0957 | Cell wall endopeptidase family M23/M37; COG2861 Uncharacterized protein conserved in bacteria; hypothetical protein. | Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | 0.431 |