STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trxBCOG0492 Thioredoxin reductase. (322 aa)    
Predicted Functional Partners:
trxA
Thioredoxin 1; COG0526 Thiol-disulfide isomerase and thioredoxins; Belongs to the thioredoxin family.
 
 0.996
ahpC
Alkyl hydroperoxide reductase subunit C-like protein; COG1113 Gamma-aminobutyrate permease and related permeases; putative proline-specific permease.
  
 
 0.937
sufS
Cysteine desulfurase SufS subfamily; Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation. Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L- selenocysteine. Selenocysteine lyase activity is however unsure in vivo.
  
 
 0.905
ybbN
COG3118 Thioredoxin domain-containing protein.
  
 
 0.823
katE
Hydroperoxidase II; Serves to protect cells from the toxic effects of hydrogen peroxide.
   
 
 0.764
ccmG
Cytochrome c-type biogenesis protein CcmG/DsbE thiol:disulfide oxidoreductase; COG0526 Thiol-disulfide isomerase and thioredoxins.
  
 
 0.762
ycbX
Flavodoxin reductases (ferredoxin-NADPH reductases) family 1; COG3217 Uncharacterized Fe-S protein.
   
 
 0.696
yfaE
2Fe-2S ferredoxin YfaE; ISSoEn2, terminal inverted repeat.
   
 
 0.660
barA
Histidine kinase; Potential frameshift: common BLAST hit: gi|261822788|ref|YP_003260894.1| glycerate kinase; glycerate kinase.
 
  
 0.606
nfuA
Fe/S biogenesis protein NfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.
  
  
 0.578
Your Current Organism:
Sodalis pierantonius
NCBI taxonomy Id: 2342
Other names: C. Sodalis pierantonius str. SOPE, Candidatus Sodalis pierantonius str. SOPE, SOPE, Sitophilus oryzae endosymbiont, Sitophilus oryzae primary endosymbiont, Sitophilus oryzae principal endosymbiont, primary endosymbiont of Sitophilus oryzae
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