STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rstA2DNA-binding transcriptional regulator RstA; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (231 aa)    
Predicted Functional Partners:
arcB
Aerobic respiration control sensor protein; COG1242 Predicted Fe-S oxidoreductase; putative Fe-S oxidoreductase.
 
 
 0.965
barA
Histidine kinase; Potential frameshift: common BLAST hit: gi|261822788|ref|YP_003260894.1| glycerate kinase; glycerate kinase.
 
 
 0.953
nuoC
Bifunctional NADH:ubiquinone oxidoreductase subunit C/D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the C-terminal section; belongs to the complex I 49 kDa subunit family.
    
   0.875
cpxA
Copper sensory histidine kinase CpxA; COG0642 Signal transduction histidine kinase.
 
 0.834
ssrA
Secretion system regulator: Sensor component; COG0642 Signal transduction histidine kinase.
 
 
 0.825
envZ
Osmolarity sensory histidine kinase EnvZ; COG0642 Signal transduction histidine kinase.
 
 0.757
phoQ
Sensor protein PhoQ.
 
 
 0.743
phoR
Phosphate regulon sensor protein PhoR (SphS); COG0642 Signal transduction histidine kinase.
 
 0.723
czcS
Sensor protein; Member of a two-component regulatory system.
 
 0.693
aaeR
Putative transcriptional regulator LYSR-type; COG0312 Predicted Zn-dependent proteases and their inactivated homologs; TldD protein part of proposed TldE/TldD proteolytic complex; Belongs to the LysR transcriptional regulatory family.
  
    0.483
Your Current Organism:
Sodalis pierantonius
NCBI taxonomy Id: 2342
Other names: C. Sodalis pierantonius str. SOPE, Candidatus Sodalis pierantonius str. SOPE, SOPE, Sitophilus oryzae endosymbiont, Sitophilus oryzae primary endosymbiont, Sitophilus oryzae principal endosymbiont, primary endosymbiont of Sitophilus oryzae
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