STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cheWPositive regulator of CheA protein activity (CheW); COG0835 Chemotaxis signal transduction protein. (163 aa)    
Predicted Functional Partners:
cheA
COG0643 Chemotaxis protein histidine kinase and related kinases.
 0.999
cheY
Chemotaxis regulator-transmits chemoreceptor signals to flagelllar motor components CheY; COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain; Chemotaxis response regulator protein-glutamate methylesterase CheB.
 
 0.974
motB2
COG1291 Flagellar motor component; Flagellar motor rotation protein MotA.
 
  
 0.939
barA
Histidine kinase; Potential frameshift: common BLAST hit: gi|261822788|ref|YP_003260894.1| glycerate kinase; glycerate kinase.
  
 
 0.928
ssrA
Secretion system regulator: Sensor component; COG0642 Signal transduction histidine kinase.
 
 
 0.859
motB1
Flagellar motor protein MotB; Potential frameshift: common BLAST hit: gi|85058003|ref|YP_453705.1| flagellar biosynthetic protein FlhB; flagellar biosynthetic protein FlhB.
 
  
 0.858
fliM2
Flagellar motor switch protein FliM; FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
 
  
 0.831
flgK2
COG1256 Flagellar hook-associated protein.
 
  
 0.830
fliM1
Flagellar motor switch protein FliM; FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
 
  
 0.792
flgK1
COG1256 Flagellar hook-associated protein.
 
  
 0.787
Your Current Organism:
Sodalis pierantonius
NCBI taxonomy Id: 2342
Other names: C. Sodalis pierantonius str. SOPE, Candidatus Sodalis pierantonius str. SOPE, SOPE, Sitophilus oryzae endosymbiont, Sitophilus oryzae primary endosymbiont, Sitophilus oryzae principal endosymbiont, primary endosymbiont of Sitophilus oryzae
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