STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yggTIntegral membrane protein YggT involved in response to extracytoplasmic stress (Osmotic shock). (179 aa)    
Predicted Functional Partners:
yggS
yggS; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.
  
  
 0.809
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
  
    0.718
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
  
    0.624
yacF
yacF; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
  
     0.571
rseB
Sigma factor RpoE negative regulatory protein RseB; COG3026 Negative regulator of sigma E activity.
  
     0.546
yafS
COG0500 SAM-dependent methyltransferases.
 
     0.517
bamE
Outer membrane protein assembly factor BamE; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
  
     0.506
ratA
ratA; COG2914 Uncharacterized protein conserved in bacteria; Belongs to the UPF0125 (RnfH) family.
  
     0.504
hisS
COG0124 Histidyl-tRNA synthetase.
 
    0.495
gshA
Glutamate--cysteine ligase; COG2918 Gamma-glutamylcysteine synthetase; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
  
    0.470
Your Current Organism:
Sodalis pierantonius
NCBI taxonomy Id: 2342
Other names: C. Sodalis pierantonius str. SOPE, Candidatus Sodalis pierantonius str. SOPE, SOPE, Sitophilus oryzae endosymbiont, Sitophilus oryzae primary endosymbiont, Sitophilus oryzae principal endosymbiont, primary endosymbiont of Sitophilus oryzae
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.