Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Score
Acid_0403Hypothetical protein; KEGG: aba:Acid345_2945 glycine cleavage H-protein. (296 aa)    
Predicted Functional Partners:
gcvT
Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine.
  
 0.984
Acid_0481
Glycine dehydrogenase (decarboxylating) beta subunit; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; glycine cleavage system P-protein; KEGG: aba:Acid345_2458 glycine dehydrogenase (decarboxylating).
  
 0.982
gcvPA
Glycine dehydrogenase (decarboxylating) alpha subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
  
 0.950
Acid_0398
PFAM: glycine cleavage H-protein; KEGG: ade:Adeh_2005 glycine cleavage H-protein.
 
     0.938
Acid_5307
TIGRFAM: 2-oxoglutarate dehydrogenase, E1 subunit; PFAM: dehydrogenase, E1 component; catalytic domain of components of various dehydrogenase complexes; Transketolase, central region; KEGG: sru:SRU_1173 2-oxoglutarate dehydrogenase, E1 component.
  
 0.893
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.876
Acid_0401
Anaerobic dehydrogenases typically selenocysteine-containing-like protein; KEGG: dvu:DVU0694 molybdopterin oxidoreductase, molybdopterin-binding subunit, putative; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
 
     0.856
Acid_0399
PFAM: Polysulphide reductase, NrfD; KEGG: dde:Dde_2935 molybdopterin oxidoreductase, transmembrane subunit, putative.
 
     0.845
Acid_0402
KEGG: dde:Dde_2932 hypothetical protein.
 
    0.821
Acid_0400
PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: dde:Dde_2934 molybdopterin oxidoreductase, iron-sulfur cluster-binding subunit, putative.
       0.773
Your Current Organism:
Solibacter usitatus
NCBI taxonomy Id: 234267
Other names: Acidobacteriaceae bacterium Ellin6076, Acidobacterium sp. Ellin6076, C. Solibacter usitatus Ellin6076, Candidatus Solibacter usitatus Ellin6076, Solibacter usitatus Ellin6076, bacterium Ellin6076
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