node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Acid_0481 | Acid_0912 | Acid_0481 | Acid_0912 | Glycine dehydrogenase (decarboxylating) beta subunit; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; glycine cleavage system P-protein; KEGG: aba:Acid345_2458 glycine dehydrogenase (decarboxylating). | TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; HI0933 family protein; KEGG: aba:Acid345_4304 dihydrolipoamide dehydrogenase. | 0.956 |
Acid_0481 | Acid_1867 | Acid_0481 | Acid_1867 | Glycine dehydrogenase (decarboxylating) beta subunit; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; glycine cleavage system P-protein; KEGG: aba:Acid345_2458 glycine dehydrogenase (decarboxylating). | PFAM: FAD dependent oxidoreductase; KEGG: aba:Acid345_3293 FAD dependent oxidoreductase. | 0.913 |
Acid_0481 | Acid_4203 | Acid_0481 | Acid_4203 | Glycine dehydrogenase (decarboxylating) beta subunit; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; glycine cleavage system P-protein; KEGG: aba:Acid345_2458 glycine dehydrogenase (decarboxylating). | PFAM: glycine cleavage H-protein; KEGG: aba:Acid345_0767 glycine cleavage H-protein. | 0.998 |
Acid_0481 | Acid_4804 | Acid_0481 | Acid_4804 | Glycine dehydrogenase (decarboxylating) beta subunit; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; glycine cleavage system P-protein; KEGG: aba:Acid345_2458 glycine dehydrogenase (decarboxylating). | L-threonine aldolase; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: lmo:lmo0305 hypothetical protein. | 0.925 |
Acid_0481 | Acid_5166 | Acid_0481 | Acid_5166 | Glycine dehydrogenase (decarboxylating) beta subunit; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; glycine cleavage system P-protein; KEGG: aba:Acid345_2458 glycine dehydrogenase (decarboxylating). | 2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.933 |
Acid_0481 | Acid_5925 | Acid_0481 | Acid_5925 | Glycine dehydrogenase (decarboxylating) beta subunit; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; glycine cleavage system P-protein; KEGG: aba:Acid345_2458 glycine dehydrogenase (decarboxylating). | L-threonine aldolase; PFAM: aminotransferase, class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: aba:Acid345_2367 threonine aldolase. | 0.925 |
Acid_0481 | gcvH | Acid_0481 | Acid_0483 | Glycine dehydrogenase (decarboxylating) beta subunit; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; glycine cleavage system P-protein; KEGG: aba:Acid345_2458 glycine dehydrogenase (decarboxylating). | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.999 |
Acid_0481 | gcvPA | Acid_0481 | Acid_0482 | Glycine dehydrogenase (decarboxylating) beta subunit; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; glycine cleavage system P-protein; KEGG: aba:Acid345_2458 glycine dehydrogenase (decarboxylating). | Glycine dehydrogenase (decarboxylating) alpha subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | 0.999 |
Acid_0481 | gcvT | Acid_0481 | Acid_0484 | Glycine dehydrogenase (decarboxylating) beta subunit; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; glycine cleavage system P-protein; KEGG: aba:Acid345_2458 glycine dehydrogenase (decarboxylating). | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.999 |
Acid_0481 | glyA | Acid_0481 | Acid_7017 | Glycine dehydrogenase (decarboxylating) beta subunit; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; glycine cleavage system P-protein; KEGG: aba:Acid345_2458 glycine dehydrogenase (decarboxylating). | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.989 |
Acid_0912 | Acid_0481 | Acid_0912 | Acid_0481 | TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; HI0933 family protein; KEGG: aba:Acid345_4304 dihydrolipoamide dehydrogenase. | Glycine dehydrogenase (decarboxylating) beta subunit; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; glycine cleavage system P-protein; KEGG: aba:Acid345_2458 glycine dehydrogenase (decarboxylating). | 0.956 |
Acid_0912 | Acid_4203 | Acid_0912 | Acid_4203 | TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; HI0933 family protein; KEGG: aba:Acid345_4304 dihydrolipoamide dehydrogenase. | PFAM: glycine cleavage H-protein; KEGG: aba:Acid345_0767 glycine cleavage H-protein. | 0.959 |
Acid_0912 | gcvH | Acid_0912 | Acid_0483 | TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; HI0933 family protein; KEGG: aba:Acid345_4304 dihydrolipoamide dehydrogenase. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.984 |
Acid_0912 | gcvPA | Acid_0912 | Acid_0482 | TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; HI0933 family protein; KEGG: aba:Acid345_4304 dihydrolipoamide dehydrogenase. | Glycine dehydrogenase (decarboxylating) alpha subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | 0.954 |
Acid_0912 | gcvT | Acid_0912 | Acid_0484 | TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; HI0933 family protein; KEGG: aba:Acid345_4304 dihydrolipoamide dehydrogenase. | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.978 |
Acid_0912 | glyA | Acid_0912 | Acid_7017 | TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; HI0933 family protein; KEGG: aba:Acid345_4304 dihydrolipoamide dehydrogenase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.927 |
Acid_1867 | Acid_0481 | Acid_1867 | Acid_0481 | PFAM: FAD dependent oxidoreductase; KEGG: aba:Acid345_3293 FAD dependent oxidoreductase. | Glycine dehydrogenase (decarboxylating) beta subunit; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; glycine cleavage system P-protein; KEGG: aba:Acid345_2458 glycine dehydrogenase (decarboxylating). | 0.913 |
Acid_1867 | Acid_4804 | Acid_1867 | Acid_4804 | PFAM: FAD dependent oxidoreductase; KEGG: aba:Acid345_3293 FAD dependent oxidoreductase. | L-threonine aldolase; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: lmo:lmo0305 hypothetical protein. | 0.904 |
Acid_1867 | Acid_5166 | Acid_1867 | Acid_5166 | PFAM: FAD dependent oxidoreductase; KEGG: aba:Acid345_3293 FAD dependent oxidoreductase. | 2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.913 |
Acid_1867 | Acid_5925 | Acid_1867 | Acid_5925 | PFAM: FAD dependent oxidoreductase; KEGG: aba:Acid345_3293 FAD dependent oxidoreductase. | L-threonine aldolase; PFAM: aminotransferase, class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: aba:Acid345_2367 threonine aldolase. | 0.919 |