| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Acid_0052 | Acid_0526 | Acid_0052 | Acid_0526 | KEGG: mja:MJ0571 aspartate kinase; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. | PFAM: homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase, NAD-binding; KEGG: mca:MCA0597 homoserine dehydrogenase. | 0.984 |
| Acid_0052 | Acid_0546 | Acid_0052 | Acid_0546 | KEGG: mja:MJ0571 aspartate kinase; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. | TIGRFAM: threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; KEGG: aba:Acid345_4034 threonine synthase. | 0.811 |
| Acid_0052 | Acid_1559 | Acid_0052 | Acid_1559 | KEGG: mja:MJ0571 aspartate kinase; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. | L-threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. | 0.839 |
| Acid_0052 | Acid_4184 | Acid_0052 | Acid_4184 | KEGG: mja:MJ0571 aspartate kinase; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.903 |
| Acid_0052 | Acid_4622 | Acid_0052 | Acid_4622 | KEGG: mja:MJ0571 aspartate kinase; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. | Homoserine O-acetyltransferase; PFAM: alpha/beta hydrolase fold; KEGG: bxe:Bxe_B0598 homoserine O-acetyltransferase; Belongs to the AB hydrolase superfamily. MetX family. | 0.918 |
| Acid_0052 | Acid_5877 | Acid_0052 | Acid_5877 | KEGG: mja:MJ0571 aspartate kinase; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. | PFAM: alpha/beta hydrolase fold; KEGG: aba:Acid345_2278 alpha/beta hydrolase. | 0.918 |
| Acid_0052 | Acid_7030 | Acid_0052 | Acid_7030 | KEGG: mja:MJ0571 aspartate kinase; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. | PFAM: homoserine dehydrogenase; homoserine dehydrogenase, NAD-binding; KEGG: ade:Adeh_3931 homoserine dehydrogenase. | 0.983 |
| Acid_0052 | metXA | Acid_0052 | Acid_1433 | KEGG: mja:MJ0571 aspartate kinase; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. | Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. | 0.991 |
| Acid_0052 | thrB | Acid_0052 | Acid_0902 | KEGG: mja:MJ0571 aspartate kinase; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.984 |
| Acid_0526 | Acid_0052 | Acid_0526 | Acid_0052 | PFAM: homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase, NAD-binding; KEGG: mca:MCA0597 homoserine dehydrogenase. | KEGG: mja:MJ0571 aspartate kinase; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. | 0.984 |
| Acid_0526 | Acid_0546 | Acid_0526 | Acid_0546 | PFAM: homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase, NAD-binding; KEGG: mca:MCA0597 homoserine dehydrogenase. | TIGRFAM: threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; KEGG: aba:Acid345_4034 threonine synthase. | 0.861 |
| Acid_0526 | Acid_1559 | Acid_0526 | Acid_1559 | PFAM: homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase, NAD-binding; KEGG: mca:MCA0597 homoserine dehydrogenase. | L-threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. | 0.842 |
| Acid_0526 | Acid_4184 | Acid_0526 | Acid_4184 | PFAM: homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase, NAD-binding; KEGG: mca:MCA0597 homoserine dehydrogenase. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.928 |
| Acid_0526 | Acid_4622 | Acid_0526 | Acid_4622 | PFAM: homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase, NAD-binding; KEGG: mca:MCA0597 homoserine dehydrogenase. | Homoserine O-acetyltransferase; PFAM: alpha/beta hydrolase fold; KEGG: bxe:Bxe_B0598 homoserine O-acetyltransferase; Belongs to the AB hydrolase superfamily. MetX family. | 0.922 |
| Acid_0526 | Acid_5877 | Acid_0526 | Acid_5877 | PFAM: homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase, NAD-binding; KEGG: mca:MCA0597 homoserine dehydrogenase. | PFAM: alpha/beta hydrolase fold; KEGG: aba:Acid345_2278 alpha/beta hydrolase. | 0.919 |
| Acid_0526 | Acid_7030 | Acid_0526 | Acid_7030 | PFAM: homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase, NAD-binding; KEGG: mca:MCA0597 homoserine dehydrogenase. | PFAM: homoserine dehydrogenase; homoserine dehydrogenase, NAD-binding; KEGG: ade:Adeh_3931 homoserine dehydrogenase. | 0.925 |
| Acid_0526 | metXA | Acid_0526 | Acid_1433 | PFAM: homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase, NAD-binding; KEGG: mca:MCA0597 homoserine dehydrogenase. | Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. | 0.956 |
| Acid_0526 | thrB | Acid_0526 | Acid_0902 | PFAM: homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase, NAD-binding; KEGG: mca:MCA0597 homoserine dehydrogenase. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.986 |
| Acid_0546 | Acid_0052 | Acid_0546 | Acid_0052 | TIGRFAM: threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; KEGG: aba:Acid345_4034 threonine synthase. | KEGG: mja:MJ0571 aspartate kinase; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. | 0.811 |
| Acid_0546 | Acid_0526 | Acid_0546 | Acid_0526 | TIGRFAM: threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; KEGG: aba:Acid345_4034 threonine synthase. | PFAM: homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase, NAD-binding; KEGG: mca:MCA0597 homoserine dehydrogenase. | 0.861 |