Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Acid_2165TIGRFAM: heavy metal sensor kinase; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; KEGG: pca:Pcar_3082 sensor histidine kinase. (514 aa)    
Predicted Functional Partners:
Acid_2164
PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: bxe:Bxe_B1389 two component heavy metal response transcriptional regulator, winged helix family.
   0.965
Acid_6178
PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: sme:SMb20671 putative sugar uptake ABC transporter periplasmic solute-binding protein precursor.
 
  
 
 0.918
Acid_2885
Multi-sensor signal transduction histidine kinase; KEGG: gsu:GSU2816 sensory box histidine kinase/response regulator; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein.
 
0.861
Acid_2802
KEGG: gsu:GSU2816 sensory box histidine kinase/response regulator; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold-3 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.
 
0.855
Acid_5477
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: gsu:GSU0451 DNA-binding response regulator.
   0.839
Acid_6895
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: gme:Gmet_3383 two component transcriptional regulator, winged helix family.
 
   0.826
Acid_3636
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: aba:Acid345_4562 two component transcriptional regulator, winged helix family.
  
   0.819
Acid_1101
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: aba:Acid345_3061 two component transcriptional regulator, winged helix family.
  
   0.818
Acid_2403
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: aba:Acid345_4168 two component transcriptional regulator, winged helix family.
  
   0.818
Acid_4320
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: ade:Adeh_0411 two component transcriptional regulator, winged helix family.
 
   0.818
Your Current Organism:
Solibacter usitatus
NCBI taxonomy Id: 234267
Other names: Acidobacteriaceae bacterium Ellin6076, Acidobacterium sp. Ellin6076, C. Solibacter usitatus Ellin6076, Candidatus Solibacter usitatus Ellin6076, Solibacter usitatus Ellin6076, bacterium Ellin6076
Server load: low (10%) [HD]