Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Acid_2245TIGRFAM: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; KEGG: aba:Acid345_2842 phosphatase KdsC. (172 aa)    
Predicted Functional Partners:
Acid_2246
PFAM: N-acetylneuraminic acid synthase, N-terminal domain; KEGG: aba:Acid345_2841 N-acetylneuraminate synthase.
   
 0.993
kdsB
3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
 
  
 0.977
Acid_6214
TIGRFAM: 2-dehydro-3-deoxyphosphooctonate aldolase; PFAM: DAHP synthetase I/KDSA; KEGG: pca:Pcar_1944 2-dehydro-3-deoxyphosphooctonate aldolase.
 
  
 0.962
Acid_7083
TIGRFAM: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; KEGG: sat:SYN_00949 3-deoxy-manno-octulosonate-8-phosphatase.
  
  
 
0.918
Acid_2500
KpsF/GutQ family protein; KEGG: eba:ebA1315 conserved hypothetical protein, KpsF/GutQ family; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS); Belongs to the SIS family. GutQ/KpsF subfamily.
 
  
 0.886
lpxK
lipid-A-disaccharide synthase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
 
   
 0.768
Acid_2240
PFAM: short-chain dehydrogenase/reductase SDR; KEGG: aba:Acid345_2846 short-chain dehydrogenase/reductase SDR; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
   
 0.701
Acid_2244
KEGG: dde:Dde_2893 hypothetical protein.
       0.675
Acid_2243
PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein; KEGG: cvi:CV3889 acetolactate synthase.
       0.660
Acid_2241
PFAM: oxidoreductase domain protein; KEGG: aba:Acid345_2847 oxidoreductase.
       0.635
Your Current Organism:
Solibacter usitatus
NCBI taxonomy Id: 234267
Other names: Acidobacteriaceae bacterium Ellin6076, Acidobacterium sp. Ellin6076, C. Solibacter usitatus Ellin6076, Candidatus Solibacter usitatus Ellin6076, Solibacter usitatus Ellin6076, bacterium Ellin6076
Server load: low (16%) [HD]