STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Acid_2760PFAM: 5'-3' exonuclease; SMART: Helix-hairpin-helix domain protein, class 2; KEGG: aba:Acid345_2424 5'-3' exonuclease. (281 aa)    
Predicted Functional Partners:
Acid_7732
DNA topoisomerase III; KEGG: cac:CAC3567 topoisomerase B; TIGRFAM: ATP-dependent DNA helicase, RecQ family; DNA topoisomerase III; PFAM: helicase domain protein; HRDC domain protein; TOPRIM domain protein; DEAD/DEAH box helicase domain protein; DNA topoisomerase, type IA, central domain protein; SMART: DNA topoisomerase I, ATP-binding; DNA topoisomerase I, DNA-binding; Toprim sub domain protein; DEAD-like helicases-like.
  
 0.983
Acid_0002
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 0.981
Acid_1441
PFAM: metallophosphoesterase; KEGG: mxa:MXAN_5467 metallophosphoesterase.
  
 0.975
Acid_7406
PFAM: DNA polymerase B, exonuclease; DNA polymerase B region; SMART: DNA-directed DNA polymerase B; KEGG: gme:Gmet_3187 DNA polymerase B, exonuclease.
  
 0.972
Acid_1698
PFAM: helicase domain protein; type III restriction enzyme, res subunit; restriction endonuclease; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: mxa:MXAN_0787 helicase, DEAD/DEAH family.
    
 0.957
Acid_3577
PFAM: DNA mismatch repair protein MutS domain protein; KEGG: ade:Adeh_1406 DNA mismatch repair protein MutS-like.
   
 0.924
mutS
DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.
   
 0.924
Acid_1699
SMART: zinc finger, RanBP2-type.
   
 0.918
mutL
DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
   
 0.918
Acid_1040
SMART: helicase c2; DEAD-like helicases-like; KEGG: aba:Acid345_4634 helicase C2.
   
 0.914
Your Current Organism:
Solibacter usitatus
NCBI taxonomy Id: 234267
Other names: Acidobacteriaceae bacterium Ellin6076, Acidobacterium sp. Ellin6076, C. Solibacter usitatus Ellin6076, Candidatus Solibacter usitatus Ellin6076, Solibacter usitatus Ellin6076, bacterium Ellin6076
Server load: low (18%) [ZH]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.