node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Acid_1310 | Acid_3945 | Acid_1310 | Acid_3945 | TIGRFAM: 4-hydroxybenzoate polyprenyltransferase, putative; PFAM: UbiA prenyltransferase; KEGG: aba:Acid345_3612 4-hydroxybenzoate polyprenyltransferase, putative; Belongs to the UbiA prenyltransferase family. | TIGRFAM: UbiD family decarboxylases; PFAM: Carboxylyase-related protein; KEGG: aba:Acid345_1967 carboxylyase-related protein; Belongs to the UbiD family. | 0.984 |
Acid_1310 | mqnA | Acid_1310 | Acid_6764 | TIGRFAM: 4-hydroxybenzoate polyprenyltransferase, putative; PFAM: UbiA prenyltransferase; KEGG: aba:Acid345_3612 4-hydroxybenzoate polyprenyltransferase, putative; Belongs to the UbiA prenyltransferase family. | Protein of unknown function DUF178; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.839 |
Acid_1310 | mqnC | Acid_1310 | Acid_3614 | TIGRFAM: 4-hydroxybenzoate polyprenyltransferase, putative; PFAM: UbiA prenyltransferase; KEGG: aba:Acid345_3612 4-hydroxybenzoate polyprenyltransferase, putative; Belongs to the UbiA prenyltransferase family. | Radical SAM domain protein; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.831 |
Acid_1310 | mqnD | Acid_1310 | Acid_6605 | TIGRFAM: 4-hydroxybenzoate polyprenyltransferase, putative; PFAM: UbiA prenyltransferase; KEGG: aba:Acid345_3612 4-hydroxybenzoate polyprenyltransferase, putative; Belongs to the UbiA prenyltransferase family. | Protein of unknown function DUF191; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily. | 0.826 |
Acid_1310 | mqnE | Acid_1310 | Acid_1309 | TIGRFAM: 4-hydroxybenzoate polyprenyltransferase, putative; PFAM: UbiA prenyltransferase; KEGG: aba:Acid345_3612 4-hydroxybenzoate polyprenyltransferase, putative; Belongs to the UbiA prenyltransferase family. | Radical SAM domain protein; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate. | 0.960 |
Acid_1310 | ubiX | Acid_1310 | Acid_7053 | TIGRFAM: 4-hydroxybenzoate polyprenyltransferase, putative; PFAM: UbiA prenyltransferase; KEGG: aba:Acid345_3612 4-hydroxybenzoate polyprenyltransferase, putative; Belongs to the UbiA prenyltransferase family. | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. | 0.982 |
Acid_2706 | Acid_3945 | Acid_2706 | Acid_3945 | PFAM: UbiE/COQ5 methyltransferase; Methyltransferase type 11; Methyltransferase type 12; KEGG: gme:Gmet_1167 ubiquinone/menaquinone biosynthesis methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family. | TIGRFAM: UbiD family decarboxylases; PFAM: Carboxylyase-related protein; KEGG: aba:Acid345_1967 carboxylyase-related protein; Belongs to the UbiD family. | 0.603 |
Acid_3944 | Acid_3945 | Acid_3944 | Acid_3945 | 3-oxoacyl-[acyl-carrier-protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. | TIGRFAM: UbiD family decarboxylases; PFAM: Carboxylyase-related protein; KEGG: aba:Acid345_1967 carboxylyase-related protein; Belongs to the UbiD family. | 0.552 |
Acid_3945 | Acid_1310 | Acid_3945 | Acid_1310 | TIGRFAM: UbiD family decarboxylases; PFAM: Carboxylyase-related protein; KEGG: aba:Acid345_1967 carboxylyase-related protein; Belongs to the UbiD family. | TIGRFAM: 4-hydroxybenzoate polyprenyltransferase, putative; PFAM: UbiA prenyltransferase; KEGG: aba:Acid345_3612 4-hydroxybenzoate polyprenyltransferase, putative; Belongs to the UbiA prenyltransferase family. | 0.984 |
Acid_3945 | Acid_2706 | Acid_3945 | Acid_2706 | TIGRFAM: UbiD family decarboxylases; PFAM: Carboxylyase-related protein; KEGG: aba:Acid345_1967 carboxylyase-related protein; Belongs to the UbiD family. | PFAM: UbiE/COQ5 methyltransferase; Methyltransferase type 11; Methyltransferase type 12; KEGG: gme:Gmet_1167 ubiquinone/menaquinone biosynthesis methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family. | 0.603 |
Acid_3945 | Acid_3944 | Acid_3945 | Acid_3944 | TIGRFAM: UbiD family decarboxylases; PFAM: Carboxylyase-related protein; KEGG: aba:Acid345_1967 carboxylyase-related protein; Belongs to the UbiD family. | 3-oxoacyl-[acyl-carrier-protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.552 |
Acid_3945 | mqnA | Acid_3945 | Acid_6764 | TIGRFAM: UbiD family decarboxylases; PFAM: Carboxylyase-related protein; KEGG: aba:Acid345_1967 carboxylyase-related protein; Belongs to the UbiD family. | Protein of unknown function DUF178; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.821 |
Acid_3945 | mqnC | Acid_3945 | Acid_3614 | TIGRFAM: UbiD family decarboxylases; PFAM: Carboxylyase-related protein; KEGG: aba:Acid345_1967 carboxylyase-related protein; Belongs to the UbiD family. | Radical SAM domain protein; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.778 |
Acid_3945 | mqnD | Acid_3945 | Acid_6605 | TIGRFAM: UbiD family decarboxylases; PFAM: Carboxylyase-related protein; KEGG: aba:Acid345_1967 carboxylyase-related protein; Belongs to the UbiD family. | Protein of unknown function DUF191; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily. | 0.781 |
Acid_3945 | mqnE | Acid_3945 | Acid_1309 | TIGRFAM: UbiD family decarboxylases; PFAM: Carboxylyase-related protein; KEGG: aba:Acid345_1967 carboxylyase-related protein; Belongs to the UbiD family. | Radical SAM domain protein; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate. | 0.783 |
Acid_3945 | ubiX | Acid_3945 | Acid_7053 | TIGRFAM: UbiD family decarboxylases; PFAM: Carboxylyase-related protein; KEGG: aba:Acid345_1967 carboxylyase-related protein; Belongs to the UbiD family. | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. | 0.996 |
mqnA | Acid_1310 | Acid_6764 | Acid_1310 | Protein of unknown function DUF178; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). | TIGRFAM: 4-hydroxybenzoate polyprenyltransferase, putative; PFAM: UbiA prenyltransferase; KEGG: aba:Acid345_3612 4-hydroxybenzoate polyprenyltransferase, putative; Belongs to the UbiA prenyltransferase family. | 0.839 |
mqnA | Acid_3945 | Acid_6764 | Acid_3945 | Protein of unknown function DUF178; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). | TIGRFAM: UbiD family decarboxylases; PFAM: Carboxylyase-related protein; KEGG: aba:Acid345_1967 carboxylyase-related protein; Belongs to the UbiD family. | 0.821 |
mqnA | mqnC | Acid_6764 | Acid_3614 | Protein of unknown function DUF178; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). | Radical SAM domain protein; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.975 |
mqnA | mqnD | Acid_6764 | Acid_6605 | Protein of unknown function DUF178; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). | Protein of unknown function DUF191; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily. | 0.856 |